research Treatment of Obstructive Sleep Apnea Improves Cardiometabolic Function in Young Obese Women with Polycystic Ovary Syndrome
Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.
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research Mechanisms of Hepatocyte Attachment to Keratin Biomaterials
Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.
research Role of Environmental Factors and Gonadotoxin Exposure in Unexplained Male Infertility
Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.
research Metabolic Dysfunction in Female Mice with Disruption of 5α-Reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
research Effect of Neurosteroid Dehydroepiandrosterone on the Higher Nervous Activity of Old Non-Human Primates
DHEA improved brain function and behavior in old monkeys and had additional health benefits.
research Exogenous Testosterone Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum Testosterone
Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
research Azathioprine
Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
research Effect of Aminopterin on Epithelial Tissues
Aminopterin effectively improves skin conditions but has toxic side effects that need careful monitoring.
research Metabolic Regulation of Stem Cells in Aging
Eating less can improve stem cell function and increase lifespan.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Traditional Uses, Phytochemistry, Pharmacology, Toxicity and Clinical Application of Traditional Chinese Medicine Cynoglossum Amabile: A Review
Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.
research Anti-Anginal and Beta-Adrenoceptor Blocking Drugs
Beta-blockers and anti-anginal medications have various side effects and interactions that require careful monitoring and individualized treatment.
research Minoxidil: A Review of Its Pharmacological Properties and Therapeutic Use
Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
research Testosterone Therapy in Women: Myths and Misconceptions
Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
research Maternal Androgen Excess Induces Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Mice Offspring
High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
research Investigation of the Cognitive Activity Between the Leaf Extracts of Eclipta Alba and Ziziphus Jujuba in Diabetic Animal Models
Ziziphus jujuba and Eclipta alba leaf extracts improve blood sugar levels and cognitive function in diabetic rats.
research Cyclosporin: Applications in Small Animal Dermatology
Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
research Ketoconazole Therapy for Women with Acne and/or Hirsutism
Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
research Gender-Affirming Hormone Therapy for Transgender Females
Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
research Cross-Species Sensitivity to a Novel Androgen Receptor Agonist of Potential Environmental Concern, Spironolactone
Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
research Roles of Steroid Sulfatase in Brain and Other Tissues
Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
research Glycolipid and Hormonal Profiles in Young Men with Early-Onset Androgenetic Alopecia: A Meta-Analysis
Young men with early hair loss have slightly worse blood sugar and fat levels, suggesting possible health risks and need for monitoring.
research Testosterone Therapy in Premenopausal Women
Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
research Calcineurin-Based Immunosuppression in Renal Transplantation: Focus on Efficacy, the Role of Steroids, and Cardiovascular Risk
Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.
research Testosterone Therapy in Men: Clinical and Pharmacological Perspectives
Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
research Propranolol in the Treatment of Infantile Hemangioma: Clinical Effectiveness, Risks, and Recommendations
Propranolol is effective and safe for treating infantile hemangioma, but more research is needed for dosing and monitoring guidelines.
research Risk Factors, Prevalence, and Diagnosis of Hutchinson-Gilford Syndrome with Special Reference to Case Reports
Hutchinson-Gilford Progeria Syndrome is a rare genetic disorder caused by a specific gene mutation, characterized by aging symptoms and managed by monitoring heart health and using low-dose aspirin.
research Treatment of Female Sexual Dysfunction in Postmenopausal Women: What Is the Evidence?
Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.
research Workup and Management of Polycystic Ovary Syndrome
The document concludes that managing PCOS involves lifestyle changes, medication, and monitoring for associated health risks.