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The document suggests a possible link between FAM111B gene mutations and increased cancer risk, particularly pancreatic cancer.

Origanum vulgare leaf extract reduces liver and kidney damage caused by finasteride in mice.

The weight loss drug Orlistat can cause liver damage and should be used with caution, especially in those with liver or kidney issues.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.

Certain liver diseases respond well to specific treatments and have varying risks for liver cancer.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Young adults who had liver disease as children often experience significant health problems and frequently need transplants.

The research suggests that immune cells and a specific type of cell death called ferroptosis are involved in Frontal fibrosis alopecia.

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

Minoxidil is better for female hair loss without hormonal issues, cyproterone acetate for those with; people with treated congenital heart disease have lower life quality; personality differs in types of infertility; oral terbinafine is best for toenail fungus; bladder training reduces incontinence; nurse clinics help with heart disease; weight loss improves body composition and liver disease; computer training cuts drug errors.

Using skin stem cells and certain molecules might lead to scar-free skin healing.

CD8+ T cells play a key role in graft-versus-host disease in certain mice models.

High doses of rosemary extract can harm the liver, kidneys, and reproductive organs in young rats.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

The pseudo 'fringe sign' can also appear in frontal fibrosing alopecia, not just in traction alopecia, showing that this condition may be more common than thought.

Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.

The conclusion is that CD90 is not a specific marker for fibroblast subtypes and better methods are needed to identify them.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

New hair loss treatments may include topical medications, injections, and improved transplant methods.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.