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Pharmacophore models can predict liver toxicity and central nervous system toxicity, but they have limitations and specific requirements.

Isotretinoin affects trace element levels and requires monitoring of liver and kidney functions.

EDA signaling is linked to skin disorders, various cancers, and liver disease.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

Some medications caused temporary health issues that improved after stopping the drugs, but two patients died from liver problems linked to carbamazepine.

Testosterone undecanoate increases lean mass and causes various physical changes in female-to-male transsexuals.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Women with PCOS often have insulin resistance, abnormal lipid levels, and a higher risk of diabetes and heart disease; lifestyle changes and medication like metformin can help manage these risks.

The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.

PCOS is a hormonal disorder causing symptoms like excess hair, acne, irregular periods, and fertility issues.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

People with Lichen Planopilaris are more likely to have autoimmune diseases, especially Systemic Lupus Erythematosus, and less likely to have diabetes and some other common conditions.

Oral tofacitinib is a promising treatment for beard hair loss in alopecia areata.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Low-dose flutamide improved hirsutism and satisfaction in women but had common side effects, causing some to stop treatment.

Insulin resistance increases the risk of developing type 2 diabetes and other health issues.

Women with PCOS often have metabolic issues like insulin resistance and a higher risk of diabetes and abnormal lipid levels.

The case emphasizes the need for careful screening in children for insulin resistance and related conditions.

Insulin resistance is linked to many health problems and is influenced by diet, genetics, and other factors.

Recognizing and treating early signs of insulin resistance can help prevent type 2 diabetes and improve life quality.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.

Most children with a common hemochromatosis genotype had elevated iron levels but no severe symptoms.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

A balanced diet and healthy lifestyle help manage PCOS symptoms.