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An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.

Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

Combining ciclosporin and simvastatin can cause severe kidney damage.

A woman developed severe kidney injury from using simvastatin with ciclosporin, highlighting the need for careful monitoring when combining these drugs.

The black orchid Brasiliorchis schunkeana produces chemicals that attract certain insects and have potential antimicrobial properties.

Minoxidil activation by hair enzymes predicts treatment success for female hair loss.

Genetic variants affect minoxidil hair loss treatment success.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Proteolytic enzymes damage hair follicles by detaching stem cells.

Inducing ferroptosis in hepatic stellate cells is crucial for treating liver fibrosis.

The enzyme myo-inositol oxygenase is not linked to the cause of polycystic ovarian syndrome.

Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

There is no significant link between alopecia areata and the PON1 enzyme polymorphisms studied.

The patient's liver did not fully grow back and she had serious temporary side effects after a very large liver surgery.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.

Alopecia patients have a less active liver monoxygenase system, which can be treated with photochemotherapy and system inducers.

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

Finasteride and methadone don't increase advanced liver disease risk in HCV+ male veterans.