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Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

Methotrexate side effects vary by race and sex.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.

Topical treatments for hair loss can be effective but need careful safety evaluation.

Flavonoids in Iraqi marshland plants have potential health benefits like antioxidant and anti-inflammatory effects.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.

The enzyme pyruvate kinase M2 helps hair regrowth and could be a potential treatment for hair loss.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.