research Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture
TNFα helps grow and maintain liver cells in 3D culture for a long time.
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research Sexuality and Polycystic Ovary Syndrome
Women with PCOS are more likely to experience sexual dysfunction, but lifestyle changes and weight loss can improve sexual function.
research Physiological Functions of PP2A: Lessons from Genetically Modified Mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
research Acquired Zinc Deficiency Dermatosis in Humans
Zinc supplements can resolve skin issues caused by zinc deficiency.
research The Bright Side of Fibroblasts: Molecular Signature and Regenerative Cues in Major Organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Misdiagnosis as Asphyxiating Thoracic Dystrophy and CMV-Associated Hemophagocytic Lymphohistiocytosis in Shwachman-Diamond Syndrome
Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.
research Finasteride-Induced Gynecomastia
Finasteride can cause enlarged breasts.
research The Biomedical Role of Zinc in the Functioning of the Human Organism
Zinc is essential for many body functions and imbalances can lead to health problems.
research Attenuation of Autoimmune Phenomena in a Patient with Autoimmune Polyglandular Syndrome Type 1
The girl's condition improved with treatment, showing no new autoimmune diseases and hair regrowth.
research Lipoatrophy and Severe Metabolic Disturbance in Mice with Fat-Specific Deletion of PPARγ
Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
research Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway
Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
research Red Ginseng Monograph
Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.
research Ginseng Phytochemicals as Therapeutics in Oncology: Recent Perspectives
Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.
research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research Controversies Regarding Transdermal Androgen Therapy in Postmenopausal Women
Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.
research Prospective Metabolic Evaluation of 150 Consecutive Patients Who Underwent Gastric Exclusion
Gastric exclusion surgery caused major weight loss and health improvements but led to some anemia and vitamin deficiencies.
research Biallelic HEPHL1 Variants Impair Ferroxidase Activity and Cause an Abnormal Hair Phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
research Zinc: A Complementary Factor in the Treatment of Chronic Hepatitis C?
Zinc supplementation may help improve treatment outcomes for chronic hepatitis C.
research Novel Aspects of Age-Protection by Spermidine Supplementation Are Associated with Preserved Telomere Length
Spermidine helps protect against aging by preserving telomere length.
research A Perspective on the Evolving Landscape in Male Reproductive Medicine
Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.
research Multiple Sclerosis Disease-Modifying Therapies: Adverse Effect Surveillance and Management
The document concludes that managing side effects of MS therapies is crucial for treatment success and patient adherence.
research Women's Health Care During the Perimenopause
The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.
research Hair Glucocorticoid Levels in Parkinson’s Disease
People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.
research Zinc Oxide Nanoparticles Fortified Biscuits as a Nutritional Supplement for Zinc Deficient Rats
Zinc oxide nanoparticle biscuits improved growth and health in zinc-deficient rats without toxicity.
research Metabolic Syndrome: A New Definition and Management Guidelines
New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.
research Polycystic Ovary Syndrome: Overview and Treatment
The document says PCOS is a common hormonal disorder in women, diagnosed by certain criteria, and managed with lifestyle changes and various medications.
research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease
Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
research Transcriptomic Profiling in Silurana Tropicalis Testes Exposed to Finasteride
Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
research Interpretation of Laboratory Data and General Physical Examination by Pharmacists
Pharmacists should interpret lab data and perform physical exams to improve patient care.
research Reversal of Androgenetic Alopecia in a Male: A Spironolactone Effect?
A man's baldness improved possibly due to a medication that blocks male hormones.