March 2025 in “MINAR International Journal of Applied Sciences and Technology” This study reviewed evidence on the role of specific genes (FKBP12, SAMAHD1, TRF2, CD155, and GATA3) in predicting how breast cancer patients might respond to adjuvant chemotherapy, aiming to monitor these markers in blood or tissue samples.
91 citations
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December 2017 in “Systems Biology in Reproductive Medicine” This meta-analysis found that lower serum SHBG levels are associated with an increased risk of PCOS, and improving SHBG levels through treatment may reduce PCOS complications.
119 citations
,
November 2014 in “Trends in Cell Biology” This review discusses the mechanisms and pathways of FGFR signalling and its roles in development, disorders, and therapeutic targeting, but reports no new clinical results.
114 citations
,
March 2018 in “PLOS Medicine” This study found that women with polycystic ovary syndrome have higher rates of nonalcoholic fatty liver disease, with androgen excess contributing to the risk.
114 citations
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January 2014 in “World Journal of Gastroenterology” This study highlights the potential increased frequency of advanced liver disease in obese PCOS patients with NAFLD and underscores the importance of lifestyle modifications as initial treatment.
28 citations
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November 2019 in “Frontiers in Endocrinology” This study found that Indian women with PCOS following a vegetarian diet had higher pro-inflammatory and lower anti-inflammatory marker levels compared to age and BMI-matched non-vegetarian counterparts.
19 citations
,
March 2007 in “Journal of diabetes science and technology” This study found that both metformin and rosiglitazone improved ovulation and insulin sensitivity in women with PCOS, with rosiglitazone showing a more pronounced increase in adiponectin levels.
November 2025 in “Scientific Reports” This study found that metabolic dysfunction-associated steatotic liver disease is linked to a higher risk of androgenetic alopecia, especially in women and individuals with certain lifestyle patterns.
September 2023 in “Ethiopian journal of health sciences” This study evaluated the effects of dry plantain leaf extract on mice infected with Plasmodium berghei, finding that the extract reduced liver oxidative stress associated with the infection.
This study found that all examined biomarkers and clinical features were elevated in systemic lupus erythematosus patients, particularly ANA and Anti-dsDNA autoantibodies, but no single biomarker was sensitive or specific enough for diagnosis.
January 2014 in “Springer eBooks” Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.
85 citations
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September 2013 in “International Journal of Molecular Sciences” This review evaluates existing research on Keratin 15 to assess its validity as a marker for epidermal stem cells, reporting no new results.
7 citations
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May 2010 in “Journal of Dermatological Treatment” This case report describes a patient with various conditions, including ulcerative colitis and azathioprine-induced liver injury, and reviews related literature on these coexisting conditions.
January 2020 in “Research Portal Denmark” This study concludes that anti-androgenic chemicals causing short anogenital distance in male fetuses also induce a feminized transcriptional profile in the perineum, implicating Wnt and estrogen signaling in the process.
26 citations
,
October 2017 in “Clinical Reviews in Allergy & Immunology” This review explores skin manifestations associated with autoimmune liver diseases and highlights known and probable links, such as vitiligo's strong association with autoimmune hepatitis.
April 2018 in “Journal of Investigative Dermatology” This study found that plasma cardiac troponin I levels were highest in subjects with alopecia areata, potentially indicating increased heart remodeling and a need for close cardiovascular monitoring in these individuals.
3 citations
,
April 2019 in “Annals of hepatology” This case report described a peanut allergy transfer from an organ donor to two transplant recipients, emphasizing the need for pre-transplant donor allergy screening.
2 citations
,
June 2012 in “Digestive Diseases and Sciences” This study suggests that finasteride use is not significantly associated with a reduced risk of advanced hepatic fibrosis or inflammation in HCV-positive males, with ethnically-divergent findings for methadone requiring further investigation.
59 citations
,
May 2017 in “Scientific reports” This study found that ZDHHC13 deficiency in mice is associated with abnormal liver function, lipid metabolism issues, and impaired mitochondrial function, highlighting ZDHHC13's regulatory role in liver metabolism.
8 citations
,
October 2023 in “Folia Histochemica et Cytobiologica” This study observed that exosomes from adipose mesenchymal stem cells overexpressing hepatocyte growth factor significantly improved liver function and reduced fibrosis in mice with experimentally induced liver injury.
1 citations
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October 2025 in “International Journal of Nanomedicine” This review explores the potential for using exosomes in treating autoimmune skin diseases and promoting skin regeneration, highlighting current applications, delivery methods, and ongoing clinical trials while also identifying challenges and future research directions within dermatology.
4 citations
,
December 2023 in “Medicine” This study found that the genes MYLK and CALD1 were expressed at lower levels in bladder cancer and osteosarcoma tissues compared to normal tissues, and their expression levels appeared to correlate with poorer survival outcomes, suggesting they may be important in disease progression and prognosis.
November 2025 in “Analytical Chemistry” This study developed an ultrahigh-power sonicator to improve protein extraction from hair shafts, followed by advanced proteomic analysis, identifying 239 differentially expressed proteins in fetal growth restriction cases compared to healthy controls, which were validated as potential biomarkers for perinatal diagnostics.
September 2024 in “Journal of Bioscience and Applied Research/Journal of Bioscience and Applied Research ” This study explored biochemical biomarkers in post-COVID-19 patients experiencing acute telogen effluvium, finding sex differences in blood characteristics and varying D-dimer levels by age, with elevated D-dimer showing correlations with inflammation markers.
September 2019 in “Journal of Investigative Dermatology” This study introduced a reproducible human model using 3D-SeboSkin technology to study hidradenitis suppurativa, allowing better maintenance of skin integrity and replication of biomarker expression patterns compared to traditional skin cultures, suggesting its value for further research.
9 citations
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August 2019 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil activation by hair enzymes predicts treatment success for female hair loss.
August 2023 in “Gadua Journal of Pure and Allied Science” This study on diabetic rats reported that Ziziphus spina-christi ethanol leaf extract significantly reduced blood glucose levels and improved liver and kidney function, suggesting possible benefits in managing diabetes symptoms in this animal model.
April 2026 in “Frontiers in Pharmacology” This review systematically evaluates Erzhi Pill's formulation, therapeutic potential, and challenges, exploring its traditional applications and modern prospects for developing integrated quality control and precise medical strategies.
432 citations
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April 2014 in “Nature communications” This study found that the maternal nutritional status during early pregnancy significantly influenced epigenetic changes in offspring, as maternal diet altered DNA methylation at human metastable epialleles.
139 citations
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November 2016 in “Journal of the American Academy of Dermatology” In this retrospective review, tofacitinib treatment was associated with clinically significant hair regrowth in most adolescent patients with alopecia areata, though limitations suggest further studies are needed to confirm these findings.