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60-90 / 1000+ resultsresearch Research Progress of Extracellular Vesicles-Loaded Microneedle Technology
Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.
![Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation](/images/research/2b7ee253-4a0e-400a-ac38-76e7bb2696d9/small/19051.jpg)
research Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation
Human skin xenografting could improve our understanding of skin development, renewal, and healing.
![Mechanisms of tolerance and potential therapeutic interventions in Alopecia Areata](/images/research/ee6e7166-f73d-4397-8e5e-f43fe18e2b44/small/35810.jpg)
research Mechanisms of tolerance and potential therapeutic interventions in Alopecia Areata
Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.
![Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress](/images/research/6ad0bdff-5107-4714-ae8f-fb35d3a0d970/small/36957.jpg)
research Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress
Gray hair can potentially be reversed, leading to new treatments.
![Characterization of X‐linked hypohidrotic ectodermal dysplasia (XL‐HED) hair and sweat gland phenotypes using phototrichogram analysis and live confocal imaging](/images/research/c5ce3258-a8af-4eb3-b97b-c0a557758072/small/19015.jpg)
research Characterization of X‐linked hypohidrotic ectodermal dysplasia (XL‐HED) hair and sweat gland phenotypes using phototrichogram analysis and live confocal imaging
People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.
![Recent advances in single-cell engineered live biotherapeutic products research for skin repair and disease treatment](/images/research/06e63a32-6f61-4cfd-ad1a-df3de3a4cd38/small/35164.jpg)
research Recent advances in single-cell engineered live biotherapeutic products research for skin repair and disease treatment
Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.
![Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate](/images/research/82a8f174-3f2c-4334-8a6c-625750102270/small/19368.jpg)
research Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
![I‐Ascorbic acid 2‐phosphate represses the dihydrotestosterone‐induced dickkopf‐1 expression in human balding dermal papilla cells](/images/research/18d492e9-5fd6-4ccb-8445-8b41b30dee2a/small/26231.jpg)
research I‐Ascorbic acid 2‐phosphate represses the dihydrotestosterone‐induced dickkopf‐1 expression in human balding dermal papilla cells
Vitamin C derivative reduces hair loss-related protein in cells.
![Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review](/images/research/1664adac-cd28-45a6-b16c-c3f862b795b7/small/15081.jpg)
research Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
![Polycystic Ovary Syndrome](/images/research/07e91823-0e73-4826-8c64-62b81254a0a2/small/14786.jpg)
research Polycystic Ovary Syndrome
Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.
![Keratinocyte Stem Cells but Not Melanocyte Stem Cells Are the Primary Target for Radiation-Induced Hair Graying](/images/research/6e413eeb-01ac-4f75-a92a-d8732dfa0162/small/19760.jpg)
research Keratinocyte Stem Cells but Not Melanocyte Stem Cells Are the Primary Target for Radiation-Induced Hair Graying
Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
research STAT3 Partly Inhibits Cell Proliferation via Direct Negative Regulation of FST Gene Expression
The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.
![Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis](/images/research/6c313764-912b-4808-9488-cf670293e03f/small/19087.jpg)
research Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.
![MALE-PATTERN HAIR LOSS — A SUPRAORBITAL NERVE ENTRAPMENT SYNDROME?](/images/research/33680f62-c768-47a5-9cd5-cba7c006036a/small/1793.jpg)
research MALE-PATTERN HAIR LOSS — A SUPRAORBITAL NERVE ENTRAPMENT SYNDROME?
Hair loss might be due to nerve issues, treatable with electric stimulation or acupuncture.
![440 Topical application of anti-cancer drug Bortezomib stimulates proliferation of follicular cells and induces expression of hair keratins via GATA-3 transcription factor](/images/research/eaa9f85b-0a28-48dd-8220-3531b4a98c93/small/29817.jpg)
research 440 Topical application of anti-cancer drug Bortezomib stimulates proliferation of follicular cells and induces expression of hair keratins via GATA-3 transcription factor
Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.
![441 RPGRIP1L facilitates desmosomal adhesion through suppressing PKCβII-mediated desmoglein endocytosis: Implication in pemphigus](/images/research/0827230e-0a82-4d94-9939-a69e76836b1c/small/29818.jpg)
research 441 RPGRIP1L facilitates desmosomal adhesion through suppressing PKCβII-mediated desmoglein endocytosis: Implication in pemphigus
RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.
![Reproductive seasonality and maturation throughout the complete life-cycle in the mouflon ram (Ovis musimon)](/images/research/306f0b29-7f7b-4adf-8aea-5ee8b1222b52/small/23290.jpg)
research Reproductive seasonality and maturation throughout the complete life-cycle in the mouflon ram (Ovis musimon)
Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.
![Cutaneous Manifestations of Mucopolysaccharidoses](/images/research/b5683ec5-7322-4320-81d0-721af66f3a24/small/34348.jpg)
research Cutaneous Manifestations of Mucopolysaccharidoses
People with Mucopolysaccharidoses often have skin problems like thick skin and extra hair, and recognizing these can help diagnose and treat the condition early.
![A microscopy-based small molecule screen in primary neurons reveals neuroprotective properties of the FDA-approved anti-viral drug Elvitegravir](/images/research/035dea74-98b6-458a-8db2-2af43325f6d7/small/12150.jpg)
research A microscopy-based small molecule screen in primary neurons reveals neuroprotective properties of the FDA-approved anti-viral drug Elvitegravir
The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.
![Phenotypic profiling of parents with cryptic nonclassic congenital adrenal hyperplasia: findings in 145 unrelated families](/images/research/a749eae1-b88b-4eab-9773-163e3961772f/small/14787.jpg)
research Phenotypic profiling of parents with cryptic nonclassic congenital adrenal hyperplasia: findings in 145 unrelated families
Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.
![The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice](/images/research/36cf50a3-4d9a-474e-ad53-0cec110e53da/small/18629.jpg)
research The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice
Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
![Minoxidil Promotes Hair Growth through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells](/images/research/aabf0b98-e7cb-4dc4-a584-8c7e86066902/small/4250.jpg)
research Minoxidil Promotes Hair Growth through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells
Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.
![3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling](/images/research/4d4ff7b6-f5d0-463f-8d0d-e7e3bead375f/small/18386.jpg)
research 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling
3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.
![Injections of platelet-rich plasma for androgenic alopecia: A systematic review](/images/research/28964314-c435-443b-8251-6b73f845f53f/small/4077.jpg)
research Injections of platelet-rich plasma for androgenic alopecia: A systematic review
PRP injections help regrow hair, reduce hair loss, and increase hair thickness, but effects decrease without ongoing treatment.
![A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4](/images/research/41f8b5d1-8a9a-4ae9-bf30-e3a14a810061/small/29851.jpg)
research A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4
The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.
![Anti-androgenic therapy with finasteride in patients with chronic heart failure – a retrospective propensity score based analysis](/images/research/8d09b1b6-aa93-4bc2-82b5-32905f26adbb/small/4578.jpg)
research Anti-androgenic therapy with finasteride in patients with chronic heart failure – a retrospective propensity score based analysis
Finasteride helps reduce heart enlargement in heart failure patients.
![Melatonin protects cochlear hair cells from nicotine‐induced injury through inhibiting apoptosis, inflammation, oxidative stress and endoplasmic reticulum stress](/images/research/28bc1e0e-e43f-464f-b48e-34b700cbe78a/small/25800.jpg)
research Melatonin protects cochlear hair cells from nicotine‐induced injury through inhibiting apoptosis, inflammation, oxidative stress and endoplasmic reticulum stress
Melatonin may protect ear cells from damage caused by nicotine.
![<i>In vivo</i> and <i>in silico</i> evaluation of the ameliorative effect of hesperidin on finasteride-induced testicular oxidative stress in Wistar rats](/images/research/7da04fd7-b467-4240-89f3-ec054323f788/small/5135.jpg)
research In vivo and in silico evaluation of the ameliorative effect of hesperidin on finasteride-induced testicular oxidative stress in Wistar rats
Hesperidin protects rat testicles from finasteride damage and improves sperm health.
![Endocrine Treatment of Transsexual Persons:An Endocrine Society Clinical Practice Guideline](/images/research/8b7c6e9d-179e-4014-a947-0d64b18180f7/small/20381.jpg)
research Endocrine Treatment of Transsexual Persons:An Endocrine Society Clinical Practice Guideline
The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.