17 citations
,
December 2019 in “Stem Cells International” This review examines the recent progress in using bioactive molecules for skin regenerative medicine and reports no new clinical results; the authors suggest this method could become a promising strategy for in situ skin regeneration.
17 citations
,
July 2018 in “International Journal of Cosmetic Science” This study found that keratin-based particles were able to recover and enhance the mechanical properties and thermal stability of virgin and overbleached Asian hair, improving its strength and smoothness by around 40%, and demonstrated safety in human skin keratinocytes.
17 citations
,
August 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study concluded that the best approach for detecting Androsta-1,4,6-triene-3,17-dione administration in horses is monitoring the metabolites M1b or M4 in urine, detectable up to 77 hours post-administration.
17 citations
,
August 2014 in “American Journal of Physiology-gastrointestinal and Liver Physiology” This study found that finasteride significantly improved motor, EEG, and cellular changes in a rat model of thioacetamide-induced hepatic encephalopathy and prevented the development of hepatic coma.
17 citations
,
January 2013 in “Indian Journal of Pharmacology” This case report highlights an interest in exploring the relationship between serum levels of sodium valproate and hair loss, though no case reports currently establish this link.
17 citations
,
August 2012 in “Archives of Pharmacal Research” Acankoreoside J from Acanthopanax koreanum may help promote hair growth.
17 citations
,
August 1983 in “Australasian Journal of Dermatology” The review says skin conditions with sterile pustules need more research for better treatments.
16 citations
,
March 2007 in “The Veterinary clinics of North America. Food animal practice” This article discusses misconceptions around mineral nutrition in beef cattle and emphasizes that sub-clinical deficiencies or toxicities, rather than overt symptoms, often cause economic losses, but it reports no new findings.
16 citations
,
August 2004 in “Tetrahedron” In this study, all stereoisomers of cyoctol were synthesized and tested, revealing that contrary to initial patent claims, cyoctol does not function as an anti-androgen.
16 citations
,
May 2003 in “International Journal of Dermatology” Trichotillomania, a disorder where people compulsively pull out their own hair, often starts around age 12, is more common in adult females, and can be treated with behavior therapy and medication.
16 citations
,
July 1996 in “Dermatologic Clinics” This article discusses common dermatologic side effects of psychopharmacologic agents such as eruptions, urticaria, and photosensitivity, but it reports no new research findings.
15 citations
,
January 2016 in “Dermatologic Clinics” This article offers strategies for managing acne effectively and safely, emphasizing treatment optimization, patient tailoring, and addressing antimicrobial resistance, but reports no new clinical results.
15 citations
,
September 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses OCD spectrum disorders with dermatological symptoms, emphasizing their clinical features, neurobiology, and treatment options, while noting the need for more controlled studies.
15 citations
,
February 2014 in “BMC Research Notes” This study found that male androgenic alopecia patients using the X5 hair laser device showed a statistically significant increase in hair growth over a 26-week period.
15 citations
,
November 1997 in “Australasian Journal of Dermatology” This report describes a case where a patient with acute generalized pustular psoriasis achieved remission using a combination of oral cyclosporin and PUVA therapy, maintaining remission 12 months after stopping treatment.
14 citations
,
October 2019 in “International Journal of Women's Health” This article discusses the clinical presentation and management challenges of menopausal acne, noting its multifactorial etiology and recommending tailored treatment approaches based on acne severity and associated features, without reporting new clinical results.
14 citations
,
February 2017 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This case report described a 12-year-old girl initially misdiagnosed with alopecia areata who showed improvement in trichotillomania symptoms after treatment with psychotropic drugs and N-acetylcysteine, highlighting the need for more research to develop standardized treatment guidelines for this chronic condition.
14 citations
,
February 2011 in “Drug Metabolism and Disposition” This study examined the pharmacokinetics of finasteride in pigs and found that ketoconazole coadministration affected its distribution across various plasma compartments, bile, and urine.
13 citations
,
January 2020 in “Neuroscience” This study found that finasteride impaired object recognition memory and altered hippocampal dendritic structures in male 3xTg-AD mice, suggesting potential sex differences in Alzheimer's disease pathology.
13 citations
,
April 2019 in “Seizure” This review found that valproic acid treatment significantly increases the risk of alopecia compared to other drugs, regardless of dose or treatment duration.
13 citations
,
February 2018 in “Plastic and Reconstructive Surgery” The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.
13 citations
,
September 2016 in “Acta Médica Portuguesa” This study found that acne prevalence among adults in Greater Porto's primary healthcare centers was 61.5%, with only 25% of those with acne seeking treatment.
13 citations
,
September 2016 in “Cosmetics” This review discusses the components and effects of various hair cosmetic procedures and explores new techniques like camouflage methods and tattoo scalp, without reporting new clinical results.
13 citations
,
January 2016 in “Journal of cosmetology & trichology” This review discusses the emerging pathophysiological factors and potential new therapies for androgenetic alopecia beyond traditional treatments, but reports no new results.
13 citations
,
January 2005 in “Chemical and Pharmaceutical Bulletin” This study reported that newly synthesized progesterone derivatives significantly reduced prostate weight in testosterone-treated hamsters, with 5alpha-reductase inhibitory activity dependent on the size of the substituent at C-17.
12 citations
,
April 2018 in “Physiology & Behavior” In this study, clozapine reduced suicide-related behaviors in a schizophrenia-like mouse model, but its effects on exploratory behavior were counteracted by the neurosteroid inhibitor finasteride.
12 citations
,
December 2017 in “Journal of biomaterials science. Polymer ed.” This study found that protein extracts from human hair demonstrated significant antioxidant abilities, protecting human dermal fibroblasts from oxidative stress, suggesting potential for biomedical applications.
12 citations
,
July 2017 in “Scientific reports” In this study, researchers developed a simple, non-invasive method to monitor circadian gene expression using whole hair root cultures, finding that elderly dementia patients' peripheral clocks still oscillate similarly to younger, healthier individuals, which suggests cellular senescence minimally affects some aspects of circadian rhythms.
12 citations
,
February 2016 in “Biochemical and Biophysical Research Communications” This study found that sulforaphane treatment enhanced hair regeneration in ob/ob mice by increasing DHT-degrading enzyme levels and lowering plasma testosterone and DHT.
12 citations
,
January 1991 in “Archives of dermatological research” Male hormones control a specific gene in hamster skin, with different hormones having varying effects.