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This review highlights that autologous platelet concentrates, particularly platelet-rich fibrin, have shown potential to enhance healing and outcomes in both dental and medical applications, including injury recovery and aesthetics.

This study investigated different centrifugation systems and found that low-speed protocols and certified centrifuges produced better-quality platelet-rich fibrin and recommended using FDA-approved glass tubes for safe and effective regenerative outcomes.

In this study, researchers found that storing hair grafts at 37°C with 10% DMEM led to better graft survival compared to other solutions and temperatures, suggesting this method may enhance graft longevity and therapeutic outcomes.

This study found that three sessions of injectable platelet-rich fibrin (i-PRF+) significantly improved hair follicle density, hair volume, and thickness, as well as patient satisfaction in women with female pattern hair loss, with only minor self-limited adverse effects reported.

In this study, significant improvements in skin density and thickness, especially around the lower eyelid, were observed across all age groups using plasma fractions from a single blood draw, indicating that the therapy's effectiveness may be age-independent.

This review summarizes the use of autologous platelet concentrates in aesthetic medicine, finding promising results for facial treatments, but highlights the need for more rigorous research due to current study limitations.

This review discusses various potential applications of platelet-rich fibrin in dermatology, but reports no clinical results and highlights the need for standardized protocols.

In this narrative review, the authors discuss regenerative substances like platelet-rich fibrin and mesenchymal stem cells in biological aesthetics, noting that while these methods show promise for regeneration, their safety, effectiveness, and durability remain uncertain due to limited and heterogeneous evidence.

This study found that platelet-rich fibrin provides more sustained therapeutic effects than platelet-rich plasma in inhibiting apoptosis and enhancing proliferation and migration of human endometrial stromal cells.

This study observed that a treatment combining platelet-rich fibrin and micrograft spray-on skin led to rapid and complete wound healing in both massive and chronic burn patients within an average of 7-10 days.

This review discusses the evolution of platelet concentrates in regenerative medicine, highlighting a proposed function-driven classification that distinguishes three generations of PCs by biological activity rather than development order, with third-generation exosome-based therapies showing superior therapeutic efficacy over earlier formulations.

This study reviews various factors affecting mesenchymal stem cell transplantation efficacy, including platelet concentrate composition, donor characteristics, and environmental influences, and examines strategies for optimizing outcomes through preconditioning and combined therapies in regenerative medicine.

This study reviewed recent literature and reported that although PRP products are recognized for benefits in dermatology, including wound care and hair growth, there remains a need for standardized protocols and consensus to enhance their acceptance in cosmetic dermatology.

This review discusses current and emerging therapies for androgenetic alopecia, emphasizing regenerative treatments and nanotechnology advancements, but it reports no new clinical results.

This review synthesizes evidence on platelet-derived bioproducts like PRP and PRF, highlighting their role in tissue regeneration and their benefits in aesthetic medicine applications such as hair restoration, scar treatment, and wound healing.

This review discusses the potential role of platelet-rich fibrin in aesthetic and dental procedures but highlights the need for more rigorous future studies to confirm its effectiveness and safety.

This review discusses the use of platelet-rich fibrin (PRF) in musculoskeletal, oral, and maxillofacial surgeries and dermatology, but reports no new clinical results; further trials are needed.

This study concluded that a hair emulgel formulation combining extracts from four medicinal plants demonstrated desirable characteristics of spreadability, viscosity, pH, and safety, making it effective, harmless, and economical for potential hair care use.

This review explains the biology and preparation of platelet-rich plasma and discusses its clinical applications in plastic surgery, but reports no new findings.

This study found that platelet-rich plasma may effectively increase hair follicle numbers in men with androgenetic alopecia, but changes in hair thickness plateaued after the second injection.

This review discusses the use of platelet-rich plasma in treating androgenetic alopecia and alopecia areata, observing overall positive clinical responses without identifiable complications, and reports no new clinical results.

Platelet-rich plasma therapy may have benefits and is generally safe, but more research is needed to confirm its effectiveness and safety.

This review found mixed evidence regarding platelet-rich plasma's effectiveness in various medical applications, noting significant limitations like small sample sizes and lack of standardization that necessitate further research.

This review discusses the molecular mechanisms and clinical applications of autologous platelet-derived products for TMJ regeneration, but reports no new clinical results.

This pilot study suggests injecting platelet-derived growth factors into the scalp may offer some clinical benefits for androgenetic alopecia, though further randomized trials are needed for confirmation.

This review discusses different preparation and application methods of platelet-rich plasma in dental regenerative medicine and reports no new results, highlighting its potential and associated controversies.

This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.

This review discusses the potential of adipose-derived tissue components like nanofat and stem cells for aesthetic rejuvenation, covering their use in hair growth, scar reduction, and more, without reporting new clinical results.

This review discusses the varied use and inconsistent reporting of platelet rich plasma in aesthetic surgery, finding that current studies lack consistent methodologies and objective evidence, and reports no new clinical results.

This review discusses the diverse applications of platelet-rich plasma in aesthetic dermatology and assesses the existing literature on its effectiveness, reporting no new clinical results.