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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

New effective scar treatments are urgently needed due to the current options' limited success.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Bioprinting could improve wound healing but needs more development to match real skin.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.