research Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
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research Antioxidants and Mitochondrial Bioenergetics: Charnoly Bodies in Neurodegenerative Diseases, Cardiovascular Disorders, and Cancer
Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research Autophagy Dysfunction: The Kernel of Hair Loss?
Manipulating cell cleanup processes could help treat hair loss.
research Overview Of Popular Cosmeceuticals In Dermatology
Many popular skincare products claim to prevent aging but lack strong evidence to prove their effectiveness and safety.
research A Guide to the Use of Bioassays in Exploration of Natural Resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research Triton Modified Polyethyleneimine Conjugates Assembled With Growth Arrest-Specific Protein 6 for Androgenetic Alopecia Transdermal Gene Therapy
The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.
research Biology of Melanocytes in Mammals
Melanocytes are important for skin and hair color and protect the skin from UV damage.
research Structure and Development of the Skin and Cutaneous Appendages
Understanding skin structure and development helps diagnose and treat skin disorders.
research Systemic Antifungals: Overview, Applications, and Costs
Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.
research Topical Use of Systemic Drugs in Dermatology: A Comprehensive Review
Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
research In-Silico Cardiac Aging Regulatory Model Including MicroRNA Post-Transcriptional Regulation
Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.
research A Computationally Inferred Regulatory Heart Aging Model Including Post-Transcriptional Regulations
Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.
research Cytostatics and Immunosuppressive Drugs: Toxicities and Management
Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Non-Viral Delivery of the CRISPR/Cas System: DNA Versus RNA Versus RNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
research Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
research Hair Microscopy: An Easy Adjunct to Diagnosis of Systemic Diseases in Children
Hair microscopy is a simple and cost-effective method to help diagnose systemic diseases in children.
research Mineral Deficiencies: A Root Cause for Reduced Longevity in Mammals
Not getting enough minerals can lead to health problems and shorter lifespans.
research The Cytology and Cytochemistry of the Wool Follicle
Wool follicles are complex, involving interactions between different cell types and structures.
research Role of Cholesterol Sulfate in Epidermal Structure and Function: Lessons from X-Linked Ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
research Cosmeceuticals in Dermatology
Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.
research Pharmacological Activity Of Cepharanthine
Cepharanthine has many medicinal uses but needs improvement for better effectiveness.
research The Transient Role of Calcium and Vitamin D During the Developmental Hair Follicle Cycle
Vitamin D and calcium are essential for normal hair growth.
research AGD1, A Class 1 ARF-GAP, Acts in Common Signaling Pathways with Phosphoinositide Metabolism and the Actin Cytoskeleton in Controlling Arabidopsis Root Hair Polarity
AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
research NF-κB in Biology and Targeted Therapy: New Insights and Translational Implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
research Exosomes Based Advancements for Application in Medical Aesthetics
Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.