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Doctors need to be better prepared to assess and treat obesity in patients.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Citrullus colocynthis has pain-relieving, anti-inflammatory, antidiabetic, and hair growth benefits, but can cause side effects like colic and diarrhea.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Early balding linked to higher heart disease risk.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.

Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Jojoba oil is highly valued for its diverse medicinal and industrial uses.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

Panax ginseng is generally safe with mild side effects and may have health benefits, but more research is needed.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Melatonin improved mental health and metabolism in women with PCOS.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.