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Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Niosomes improve minoxidil skin delivery for hair loss treatment.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

PEVs improve minoxidil skin penetration, increasing hair growth.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.