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The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

Proper nutrition can help manage PCOS symptoms and improve overall health.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Some skin diseases and their treatments can negatively affect male fertility.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Using neurohormones to control keratin can lead to new skin disease treatments.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Irregular menstrual cycles in teenagers are linked to a higher risk of polycystic ovary syndrome and metabolic syndrome.

Combining Traditional Chinese Medicine and Western medicine can improve symptoms, hormone levels, and pregnancy outcomes in Polycystic Ovary Syndrome patients, but more research is needed.

Proper care and diet are crucial to prevent health issues in gerbils.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.