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Human skin has less GDNF and its receptor with age.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Ring Chromosome 11 may be linked to conditions like early puberty, excessive hair growth, hair loss, and type 2 diabetes.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The research identified key proteins that affect wool fiber thickness in Angora rabbits.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Atopic dermatitis may have genetic causes and can be treated with pharmacologic methods, glycerin creams, and controlling Staphylococcus aureus colonization.

Men with Frontal fibrosing alopecia typically lose hair on the front scalp and sometimes on sideburns and upper lip, with treatments showing varied success.

Healthy lifestyle changes can significantly improve skin health as you age.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Keratin proteins are crucial for hair structure and strength.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

Acne in dark skin is influenced by environmental factors and can lead to hyperpigmentation, with various treatment options available.

Some women with PCOS have rare genetic variants linked to the condition.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Adding insulin-like growth factor 1 and bone marrow-derived stem cells to a collagen-chitosan scaffold helps wounds heal faster and regrows hair follicles.

People with Alopecia Areata are more likely to have prediabetes and obesity.

Caffeine may help with hair loss, but more research is needed to confirm its effectiveness.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.

Some wound-healing cells can turn into fat cells around new hair growth in mice.