research Testosterone Therapy in Women: Myths and Misconceptions
Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
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research Lymphoid Enhancer-Binding Factor-1 Interacts with the DNA-Binding Domain of the Vitamin D Receptor
LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
research Approach to the Management of Patients With Hidradenitis Suppurativa: A Consensus Document
The consensus document recommends a comprehensive treatment plan for Hidradenitis Suppurativa, including various medications, surgery, lifestyle changes, and the need for more research and resources.
research Clinical Efficacy and Safety of Low-Dose Flutamide Alone and Combined with an Oral Contraceptive for the Treatment of Idiopathic Hirsutism
Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.
research The Bright Side of Fibroblasts: Molecular Signature and Regenerative Cues in Major Organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research What Every Physician Should Know About Polycystic Ovary Syndrome
Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.
research The Frequency of Metabolic Syndrome Is Higher Among Brazilian Women With PCOS, Menstrual Irregularity, and Hyperandrogenism
Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.
research Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine
Caffeine applied to the scalp can protect hair follicles from UV damage.
research Experimental and Clinical Pharmacology of Ziziphus Jujuba Mills
Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.
research Cardiovascular Risk Factors and Events in Women with Androgen Excess
Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
research Metabolic Aspects of Different Phenotypes of Polycystic Ovary Syndrome: Iranian PCOS Prevalence Study
The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.
research Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine
Hair follicles are valuable for regenerative medicine and wound healing.
research CAG Repeat Testing of Androgen Receptor Polymorphism: Is This Necessary for the Best Clinical Management of Hypogonadism?
Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
research Insulin Resistance and the Long-Term Consequences of Polycystic Ovary Syndrome
Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.
research Polycystic Ovarian Syndrome: A Comprehensive Review of Symptoms, Diagnosis, and Management
PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.
research Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair
The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
research The 2018 Revision to the Process of Care Model for Evaluation of Erectile Dysfunction
The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.
research Exogenous and Endogenous Lipids of Human Hair
Removing external lipids from hair reduces moisture and increases strength, while removing internal lipids decreases water permeability.
research Contraceptive Use in Acne
Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.
research Testosterone Implants in Women: Pharmacological Dosing for a Physiologic Effect
Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
research Getting Under the Skin of Hair Aging: The Impact of the Hair Follicle Environment
Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research Topical Use of Systemic Drugs in Dermatology: A Comprehensive Review
Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
research Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells
PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
research Endocrine and Reproductive Effects of Polycystic Ovarian Syndrome
Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.
research Dermatological Problems of Puberty
Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.
research Finasteride Improves Motor, EEG, and Cellular Changes in Rat Brain in Thioacetamide-Induced Hepatic Encephalopathy
Finasteride helps brain function in rats with liver-related brain issues.
research Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
research Cross-Sex Hormone Therapy in Australia: The Prescription Patterns of Clinicians Experienced in Adult Transgender Healthcare
Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.