research Scalp Sebaceous Physiology
The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.
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research Sjogren-Larsson Syndrome: Case Study of a 9-Year-Old Boy
A boy with Sjogren-Larsson syndrome has skin and muscle symptoms due to a specific enzyme deficiency.
research Sebocytes’ Makeup: Novel Mechanisms and Concepts in the Physiology of the Human Sebaceous Glands
Hormones and signaling pathways control sebaceous gland function and could help treat acne.
research Evaluation of New Pregnane Derivatives as 5α-Reductase Inhibitors
New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
research Rodent Models in Placental Research: Implications for Fetal Origins of Adult Disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis
Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
research Topical Spironolactone in the Treatment of Ocular Graft-Versus-Host Disease
Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.
research Molecular Interactions of Natural and Synthetic Steroids in Female Hamsters’ Flank Organs
Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
research Convergent Decay of Skin-Specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.
research Effect of Carbamates on mRNA Encoding Lipid Enzymes in Hamster Flank Organs
Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.
research A Guide to Studying Human Dermal Adipocytes In Situ
The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
research From Stem Cells Protection to Skin Microbiota Balance: Orobanche Rapum Extract, a New Natural Strategy
Orobanche rapum extract rejuvenates skin and protects skin bacteria, leading to healthier skin.
research Expression of Steroidogenic Enzymes in Human Sebaceous Glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
research Y27632 Promotes Proliferation via EGFR Signaling in a Newly Isolated and Characterized Human Primary Sebocyte Cell Line
Y27632 increases cell growth through EGFR signaling, not ROCK1/2.
research Changes in the Aging Dermal Hair Follicle Environment in Female Scalp
Aging causes changes in scalp cells that can negatively affect hair health.
research Human Scalp Skin as an Abundant and Accessible Source for Eccrine Sweat Gland Isolation and Organ Culture
Researchers found a new way to isolate sweat glands from the scalp for study and culture.
research Human Hair Follicle Stem/Progenitor Cells Express Hypoxia Markers
Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
research Ionizing Radiation Triggers Dedifferentiation of Outer Root Sheath Cells Into Stem Cell-Like Progenitors for Hair Follicle Regeneration
research Molecular Network of Smads and Id2 Genes in Hair Follicle Stem Cells Regulation
The BMP/Smads pathway and Id2 gene control hair follicle stem cells, affecting their rest and growth phases.
research The Interplay Between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation
Finasteride in male rats causes liver and metabolic issues in their offspring.
research Three-Dimensional Imaging of Tight Junction Network Across Multiple Layers of Human Epidermis by Array Tomography Using Backscattered Electron-Mode Scanning Electron Microscopy
The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.
research The Human Sebocyte Culture Model Provides New Insights Into Development and Management of Seborrhoea and Acne
The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.
research Mice Lacking the Epidermal Retinol Dehydrogenases SDR16C5 and SDR16C6 Display Accelerated Hair Growth and Enlarged Meibomian Glands
Mice without certain skin enzymes have faster hair growth and bigger eye glands.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research Lymphatic Vessel: Origin, Heterogeneity, Biological Functions, and Therapeutic Targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.
research Acne Protection: Measures and Miseries
Acne can be managed with various treatments and requires psychological support due to its emotional impact.
research Estrogen Functions in Skin and Skin Appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research A Folliculocentric Perspective of Dandruff Pathogenesis: Could a Troublesome Condition Be Caused by Changes to a Natural Secretory Mechanism?
Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.
research Vitamin D and the Skin: A Review for Dermatologists
Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.
research Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin
PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.