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720-750 / 1000+ results![The JAK/STAT signaling pathway: from bench to clinic](/images/research/2bd71fdd-78cc-478e-b70f-6d8d485cb0f1/small/17075.jpg)
research The JAK/STAT signaling pathway: from bench to clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research The complex relationship between TFEB transcription factor phosphorylation and subcellular localization
Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.
![Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities](/images/research/124bc08b-01e5-4be8-bfde-baf6761ad2a6/small/19216.jpg)
research Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Understanding, recognizing, and managing toxicities of targeted anticancer therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System
Cannabinoids may help treat various skin conditions.
![Intracrine androgen biosynthesis, metabolism and action revisited](/images/research/f125b0de-3ea8-49d8-9709-b4c930631e8d/small/20931.jpg)
research Intracrine androgen biosynthesis, metabolism and action revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
![Advances in Chitosan-Based Nanoparticles for Drug Delivery](/images/research/58cc07b9-2c9d-4365-877c-d4a97264c229/small/13170.jpg)
research Advances in Chitosan-Based Nanoparticles for Drug Delivery
Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
research Defining the Cellular Environment in the Organ of Corti following Extensive Hair Cell Loss: A Basis for Future Sensory Cell Replacement in the Cochlea
The conclusion is that genetic differences affect how the cochlea heals after hair cell loss, which may challenge the creation of hearing loss treatments.
research Bimatoprost in the treatment of eyelash hypotrichosis
Bimatoprost is effective for growing longer, thicker, and darker eyelashes.
![Production-scale fibronectin nanofibers promote wound closure and tissue repair in a dermal mouse model](/images/research/80ffc25a-1733-4dc6-847e-a946f1708cb4/small/12719.jpg)
research Production-scale fibronectin nanofibers promote wound closure and tissue repair in a dermal mouse model
Large-scale fibronectin nanofibers help heal wounds and repair tissue in a skin model of a mouse.
![GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects](/images/research/bafe4188-5b7b-46ca-9bf5-e04734a7a165/small/13144.jpg)
research GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects
GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
![Targeting integrin pathways: mechanisms and advances in therapy](/images/research/e990b25e-03a3-4ba7-b9e2-7e002829fe73/small/16752.jpg)
research Targeting integrin pathways: mechanisms and advances in therapy
New therapies are being developed that target integrin pathways to treat various diseases.
![Therapeutics for COVID-19 and post COVID-19 complications: An update](/images/research/5d479716-f97b-4a45-b185-7763caaea966/small/23736.jpg)
research Therapeutics for COVID-19 and post COVID-19 complications: An update
New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.
![Macrophage-Derived Extracellular Vesicle Promotes Hair Growth](/images/research/da79aefc-3cbc-4f01-ab55-9bf2e58ca321/small/20862.jpg)
research Macrophage-Derived Extracellular Vesicle Promotes Hair Growth
Special cell particles from macrophages can help hair grow.
research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata
MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
research Human epidermal neural crest stem cells as a source of Schwann cells
Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.
research A Review of Androgen‐Progestin Regimens for Male Contraception
Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.
![Estrogen Leads to Reversible Hair Cycle Retardation through Inducing Premature Catagen and Maintaining Telogen](/images/research/73db996e-fb2c-4ad2-b5ee-a9ab871dd2e0/small/26573.jpg)
research Estrogen Leads to Reversible Hair Cycle Retardation through Inducing Premature Catagen and Maintaining Telogen
Estrogen can temporarily slow down hair growth but this can be reversed.
![Proxalutamide Significantly Accelerates Viral Clearance and Reduces Time to Clinical Remission in Patients with Mild to Moderate COVID-19: Results from a Randomized, Double-Blinded, Placebo-Controlled Trial](/images/research/9abd8d74-bbe4-4bf0-9019-3b61af4d4cd3/small/17281.jpg)
research Proxalutamide Significantly Accelerates Viral Clearance and Reduces Time to Clinical Remission in Patients with Mild to Moderate COVID-19: Results from a Randomized, Double-Blinded, Placebo-Controlled Trial
Proxalutamide helps COVID-19 patients get rid of the virus faster and recover quicker.
research SIRT 7 activates quiescent hair follicle stem cells to ensure hair growth in mice
SIRT7 protein is crucial for starting hair growth in mice.
![Resistance to the Insulin and Elevated Level of Androgen: A Major Cause of Polycystic Ovary Syndrome](/images/research/46d0c7f8-b9a4-4b0d-a897-95807e4c0709/small/20766.jpg)
research Resistance to the Insulin and Elevated Level of Androgen: A Major Cause of Polycystic Ovary Syndrome
Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
research Thymol-loaded PLGA nanoparticles: an efficient approach for acne treatment
Thymol-loaded nanoparticles are a promising, natural treatment for acne that avoids antibiotics and preserves healthy skin bacteria.
research Direct Vasodilators and Sympatholytic Agents
Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
![A systematic summary of survival and death signalling during the life of hair follicle stem cells](/images/research/6fa152d5-8ca5-4210-b7e9-b55b8b41cf6a/small/13195.jpg)
research A systematic summary of survival and death signalling during the life of hair follicle stem cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Adipokines in the Skin and in Dermatological Diseases
Adipokines affect skin health and could be targeted for treating skin diseases.
![Concise Review: Human Dermis as an Autologous Source of Stem Cells for Tissue Engineering and Regenerative Medicine](/images/research/6ebe8063-686b-4bd6-bae1-aadbe2bf4f75/small/12809.jpg)
research Concise Review: Human Dermis as an Autologous Source of Stem Cells for Tissue Engineering and Regenerative Medicine
Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
![The 3D Bioprinted Scaffolds for Wound Healing](/images/research/cf2a51b2-af3c-40de-a9aa-d6cf6f4f88ec/small/19198.jpg)
research The 3D Bioprinted Scaffolds for Wound Healing
3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
![Platelet-derived bio-products: Classification update, applications, concerns and new perspectives](/images/research/51d4a8e4-337b-47e6-b027-3395ab634f0b/small/17519.jpg)
research Platelet-derived bio-products: Classification update, applications, concerns and new perspectives
Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.
![Mesenchymal Stromal Cell-Conditioned Medium for Skin Diseases: A Systematic Review](/images/research/6767f9e8-43d9-48b9-890c-c9226aae9c32/small/21420.jpg)
research Mesenchymal Stromal Cell-Conditioned Medium for Skin Diseases: A Systematic Review
The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.