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JAK inhibitors help with skin conditions but need more research on dosing and safety.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

The study found no common cause for a girl's crystalline cataract and uncombable hair, suggesting their co-occurrence might be coincidental.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Tamoxifen can cause total hair loss but its benefits outweigh this side effect.

The symposium concluded that a specific lipid might cause hair loss, inflammation is a key factor, and stem cells in bald scalps aren't working right, suggesting new treatment targets.

Adapalene 0.1% effectively reduces acne by decreasing comedones and altering skin properties.

TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.

Autoimmune and metabolic issues are linked, and treating one may worsen another.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.

Hair loss may signal metabolic problems and increased risk of heart disease, suggesting people with hair loss should be checked for these issues.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Tailor treatments for vitiligo to patient needs for best results.

Inflammation and Demodex mites might contribute to hair loss, and targeting them could help treat it.

Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.

Hypothyroidism in dogs is usually caused by immune system issues or gland atrophy, affects middle-aged purebreds most, and is treatable with medication.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

A patient produced cortisol after adrenalectomy, possibly due to residual tissue or other body parts making steroids.

The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.

Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

Lifestyle changes like diet and exercise are key for treating overweight women with polycystic ovary syndrome.

Low-level laser therapy helps hair growth and reduces hair loss with few side effects.