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European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Key genes are crucial for Drosophila wing development and could be insecticide targets.

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Certain hormone treatments can improve acne and related conditions in women.