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Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Fenugreek seed extract in a nanoparticle gel could be a promising new treatment for hair loss.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

Different types of PCOS in Chinese Han women show varying levels of male hormone and metabolic issues.

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

Fish oil improves skin health in people with diabetes and high cholesterol.

Ethosomes improve drug delivery through the skin but may have side effects like irritation.

Coenzyme Q10 helps reduce aging in human hair.

Topical retinoids effectively improve photodamaged skin.

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

PRP heals pockmarked skin better than salmon DNA serum.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.

Chitosan slows root hair growth and causes a buildup of callose at low concentrations, but at high concentrations, it only inhibits growth without callose buildup.

The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

PAI-2 helps in the maturation and protection of hair and nail cells.

Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.

Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.