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Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Fat cells are important for tissue repair and stem cell support in various body parts.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The document concludes that effectively managing PCOS requires a multifaceted approach.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

People with late-stage HIV-1 often experience a specific type of hair loss linked to multiple factors, including nutritional issues and immune responses.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

Arctiin helps protect hair cells from damage and death caused by oxidative stress.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

Obesity increases the risk of skin infections, inflammatory conditions, and melanoma, but not basal cell carcinoma.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

Alternative treatments show promise for hair growth beyond traditional methods.

Found different long non-coding RNAs in balding Chinese men, which may help create new treatments.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

Hesperidin protects rat testicles from finasteride damage and improves sperm health.