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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Early balding in young Indian men may indicate a higher risk of metabolic syndrome and potential heart disease.

Men with early-onset hair loss have more heart disease risk factors.

Iris germanica rhizome-derived exosomes help protect skin cells from oxidative stress and aging.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Women with pattern hair loss often have higher blood sugar, cholesterol, blood pressure, and waist size, suggesting a link between hair loss and metabolic syndrome.

Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.

Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.

Early recognition and treatment of Peripheral Arterial Disease is crucial to improve survival and health outcomes.

Honey and bee pollen can help reduce menopausal symptoms in breast cancer patients.

Women with PCOS have more Bifidobacterium in their gut compared to those without PCOS.

Metformin is less effective in men with early-onset hair loss.

Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Most adult females with acne do not have hormonal imbalances, but some show signs of excess male hormones.

The study found that PCOS affects about 6.5-6.8% of women in both urban and rural areas of Telangana, India, and highlighted the importance of lifestyle changes for management.

Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.

Testosterone's muscle-building effects do not require its conversion to DHT.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

People with Lichen Planus, especially with mucosal involvement, are more likely to have Metabolic Syndrome, which increases their risk for heart disease and diabetes.

Acne is an important sign of androgen excess disorders in women.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.