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Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

PEVs improve minoxidil skin penetration, increasing hair growth.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Oxidative stress contributes to hair graying and loss as we age.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Activating TRPV3 stops human hair growth.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Wool follicles are complex, involving interactions between different cell types and structures.