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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.

Niosomes improve minoxidil skin delivery for hair loss treatment.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.