15 citations
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May 2016 in “Die Pharmazie” This study found that nanostructured lipid carriers provided better skin-targeted delivery and drug loading for lidocaine than nanoethosomes, indicating improved local anesthetic efficacy in vitro.
12 citations
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January 2018 in “Journal of Drug Delivery Science and Technology” This study developed solid lipid nanoparticles for effective delivery of shRNA-encoding plasmids, showing reduced 5α-reductase levels in DU-145 cells without significant cytotoxicity.
2 citations
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August 2021 in “Journal of pharmaceutical research international” This study concluded that fenugreek seed extract loaded solid lipid nanoparticles demonstrated enhanced skin retention and extended release, suggesting potential as a future alternative treatment for alopecia.
December 2024 in “International Journal of Drug Delivery Technology” This study reports that a novel Nano-Structured Lipid Carrier system for delivering dutasteride may enhance its anticancer effects while reducing systemic side effects in clinical settings.
March 2024 in “Bioimpacts” In this study, curcumin-loaded nanoparticles with a size of 400 nm showed optimal accumulation in human hair follicles after seven days, although mouse models differed significantly in penetration and retention, indicating limitations in their suitability for follicular drug delivery studies.
March 2020 in “Journal of the turkish academy of dermatology” In this study, no significant difference was found in serum triglyceride and HDL cholesterol levels between male patients with androgenetic alopecia and those without.
84 citations
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April 2013 in “Applied Microbiology and Biotechnology” This review discusses the current research and development of mannosylerythritol lipids, particularly focusing on their potential commercial applications in cosmetics; it reports no new results.
47 citations
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April 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that dutasteride-loaded nanostructured lipid carriers coated with a stearic acid-chitosan oligomer are stable, less cytotoxic, and suitable for topical delivery to promote hair growth.
3 citations
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May 2019 in “Journal of Cosmetic Dermatology” This study found that a 12-week supplementation with MePL, a solution of miliacin encapsulated within polar lipids, significantly reduced hair density in the telogen phase and improved scalp dryness and hair brightness in women with telogen effluvium.
2 citations
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January 2013 in “Hair therapy & transplantation” This article discusses the link between hair loss and metabolic syndrome and emphasizes the need for monitoring these patients for cardiovascular disease risk, but it reports no new trial data.
July 2024 in “Annals of Phytomedicine An International Journal” In this study, the authors reviewed various herbal ingredients used in hair care products and found that components like aloe vera, hibiscus, amla, and fenugreek have traditional and scientifically validated benefits for addressing hair issues such as hair loss, dandruff, and damage.
2 citations
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December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that SYP123 and VAMP727 are involved in the secretion and transport of inner cell wall components, which is crucial for hardening the root hair shank in Arabidopsis.
June 2023 in “Sains Malaysiana” This study evaluated the effectiveness and safety of a cinchonine nanostructured lipid carrier serum for hair growth in mouse models, finding that it significantly increased hair length and enhanced follicle penetration compared to controls, with no notable irritation observed.
June 2022 in “Research Square (Research Square)” In this study, higher DHA/omega-6 fatty acid ratios were linked to increased social impairment in individuals with autism, alongside lower antioxidant enzyme levels and higher markers of lipid peroxidation.
3 citations
,
February 2019 in “Animal biotechnology” In this study, the PLP2 gene was found to promote secondary hair follicle development in Liaoning cashmere goats, with its expression negatively regulated by melatonin and potentially affecting follicle development via the BMP pathway.
December 2025 in “Scientific Reports” In this study, cedrol was found to reduce lipid accumulation in the liver and adipose tissues of dexamethasone-treated mice by antagonizing glucocorticoid receptors, suggesting its potential utility in treating dexamethasone-induced lipid metabolism disorders.
November 2025 in “Advances in Education Humanities and Social Science Research” This review reports that certain chemical ingredients in cosmetics are linked to various health issues, including cancer and reproductive disorders, and highlights concerns about their safety, advising careful selection and use to mitigate potential risks to human health.
This study examined hair mineral and free amino acid components in various diseases and found that when using effect size analysis, specific components related to diabetes and other conditions were identified, suggesting their potential as novel health indicators.
January 2013 in “Sen'i Gakkaishi” This study found that microfibrils play a crucial role in shaping permanent waves by thioglycolic acid, and treating damaged hair with hydrolyzed keratin improved both waving efficiency and hair damage.
282 citations
,
April 2007 in “Journal of Agricultural and Food Chemistry” This study found that apple polyphenol extract, particularly oligomeric procyanidins, inhibited pancreatic lipase activity and reduced triglyceride absorption in both mice and humans.
31 citations
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September 2015 in “BJUI” This study found that men aged 50 and older with clinical benign prostatic hyperplasia have a significantly higher prevalence of metabolic syndrome than those without the condition in the UK primary care population.
21 citations
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August 2014 in “Gynecological Endocrinology” In this study, hs-CRP levels were not significantly associated with PCOS among Indian adolescent women, but showed a positive correlation with body mass index.
20 citations
,
March 2023 in “Drug Delivery and Translational Research” This study found that a lacticin 3147 solid lipid nanoparticle gel demonstrated potent and sustained antimicrobial activity against S. aureus, including MRSA, in ex vivo S. aureus-infected pig skin.
5 citations
,
March 2024 in “Acta Scientiarum Polonorum Technologia Alimentaria” This study synthesized existing research on 11 tropical seed varieties, underscoring their potential in food, pharmaceutical, and agricultural industries due to their phytochemicals and nutrients, such as phenolics and vitamins, which could reduce waste and support sustainable practices.
2 citations
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June 2016 in “Journal of skin and stem cell” This study found that wet cupping blood differs significantly from venous blood in metabolite profiles, implying distinct biochemical pathways may be involved.
6 citations
,
January 2012 in “Breast cancer” This study suggests that breast cancer-associated phospholipids may alter the X-ray diffraction pattern of hair, potentially enabling the development of a sensitive and specific screening test for breast cancer.
6 citations
,
January 2020 in “The Aging Male” In this study, five-year testosterone replacement therapy improved fasting blood sugar, HbA1c, and triglyceride levels in Japanese hypogonadal men without significantly affecting prostate-specific antigen levels.
2 citations
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January 2022 in “Journal of Oleo Science” This study found that oil from CG17 garden cress seeds had higher amounts of β-carotenoids, tocopherols, and vitamins compared to other genotypes, with varying physiochemical properties across all seeds.
1 citations
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January 2026 in “Frontiers in Bioengineering and Biotechnology” This review discusses various nanocarriers for gene and genome editing therapies, highlighting that ionizable lipid nanoparticles show advanced delivery performance, while emerging polymer-based and exosome-inspired carriers are rapidly advancing for targeted applications.
This study utilized a mouse model of traumatic brain injury to reveal that acute neurotrauma triggers widespread lipid metabolism reprogramming and storage lipid accumulation in microglial and monocyte populations, leading to lysosomal dysfunction, inhibited autophagy, and exacerbated inflammation through a pathological feedback loop.