18 citations
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November 2019 in “Journal of Physics Conference Series” This study characterized human Wharton's Jelly Mesenchymal Stem Cells (hWJ-MSCs) isolated from umbilical cords using explant and enzymatic methods, finding both methods yielded high-purity cells capable of differentiating into adipocyte, chondrocyte, and osteocyte lineages, showing promise for regenerative medicine applications.
In this study, researchers found that bulge cells cultured from rat hair follicles demonstrated stem cell characteristics and could differentiate into neural and glial lineages.
10 citations
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November 2010 in “Pigment Cell & Melanoma Research” This study found that epidermal melanocytes can regenerate hair follicles, whereas non-cutaneous or dermal melanocytes cannot, suggesting two distinct melanocyte lineages with potential implications for melanocyte-related diseases.
6 citations
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November 2020 in “Molecular and Cellular Endocrinology” This study found that androgens downregulate BMP2 in dermal papilla cells, inhibiting hair follicle stem cell differentiation, while BMP2 addition may restore hair lineage differentiation through the Wnt/β-catenin pathway.
4 citations
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May 2023 in “Pigment Cell & Melanoma Research” In this study, researchers found that deleting the Bmi1 gene in murine melanocytes caused premature hair greying and loss of melanocyte lineage cells, highlighting BMI1's role in protecting melanocyte stem cells from stress and oxidative damage.
1 citations
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September 2025 in “International Journal of Molecular Sciences” This study found that primary stem cells from concentrated growth factor can differentiate into adipogenic, endothelial, and neuronal lineages in vitro, suggesting potential for use in regenerative therapies.
1 citations
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January 2018 in “Stem cell biology and regenerative medicine” This review discusses the roles of DNA methylation in skin development and regeneration, highlighting its impact on embryonic skin lineage, homeostasis, and potential therapeutic targets, but reports no new clinical results.
April 2017 in “Journal of Investigative Dermatology” This study reports a new optimized protocol for isolating and labeling single cells from neonatal mouse skin, enabling high-quality single cell RNA sequencing for lineage-specific cell analysis.
May 2015 in “Journal of The American Academy of Dermatology” This study suggests that blood microarray biomarkers may help predict individual treatment response in psoriasis patients, highlighting a distinct blood signature related to inflammation, interferon, and myeloid lineage transcripts.
June 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that Lrig1-positive cells in mouse epidermis are a previously unidentified source of adult interfollicular epidermal stem cells, which can contribute to sebaceous gland and epidermal lineage formation.
This study reviewed the evolution of hair transplantation techniques, particularly FUE and FUT, and found that both methods offer satisfactory outcomes for alopecia, though FUE is preferred for its less invasive nature, while FUT is better suited for larger areas despite a linear scar.
7 citations
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January 1966 in “Archives of Dermatology” The method accurately measures hair growth with minimal risk and is better than other methods.
14 citations
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July 2001 in “American Journal of Human Genetics” Haplogroup X found in Altaian population supports Amerindian origin.
3 citations
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April 2010 in “The FASEB Journal” This study found that estrogen, through estrogen receptors, can regulate the expression of the HOXC13 gene involved in hair follicle development, with MLL3 histone methylase playing a collaborative role.
2 citations
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April 2024 in “Journal of Dermatological Science” This study suggests that the MLKL-targeting inhibitor Necrosulfonamide promotes hair growth and counteracts DHT inhibition by activating Wnt signaling in hair follicle cells, revealing potential avenues for anti-alopecia drug development.
44 citations
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January 1999 in “Dermatology” This article reviews different perspectives on nevus comedonicus, discussing its classification and potential associations with systemic findings, but it reports no new results.
February 2021 in “Aesthetic Cosmetology and Medicine” This study suggests that glycosaminoglycans, like hyaluronic acid obtained biotechnologically, are safe for topical cosmetic use, enhancing skin and hair conditions by supporting cell renewal, stimulating hair growth, and aiding in the treatment of scalp issues such as seborrhea and androgenetic alopecia.
April 2023 in “Journal of Investigative Dermatology” This study reports that CD200R expression is significantly reduced in a mouse model of scarring alopecia, suggesting a potential role for this pathway in immune regulation and hair follicle protection.
September 2019 in “Journal of Investigative Dermatology” This study suggests that human skin contains distinct fibroblast subsets with unique expression profiles and functions, which can be isolated to investigate their role in skin pathogenesis.
7 citations
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June 1978 in “Archives of Dermatology” This article describes a case in which a gymnast's hair loss pattern improved after she stopped using the balance beam, suggesting the hair loss may have been due to traction from her gymnastics routine.
March 1997 in “The American Journal of Cosmetic Surgery” A new hair transplant method showed promising results and a study found how deep a CO₂ laser can penetrate skin.
2 citations
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September 2021 in “Cutis” Eating shiitake mushrooms caused a man to develop a rash similar to a skin condition known as AGEP.
1 citations
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January 2009 In this case report, a 25-year-old man with nevus comedonicus showed no improvement from keratolytics and topical tretinoin, but had success with surgical excision of the lesions.
1 citations
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November 1992 in “Indian Dermatology Online Journal” This review discusses the use of follicular unit extraction for hair restoration, particularly body hair transplantation, and highlights its potential as an alternative donor source in advanced baldness cases, but reports no new clinical findings.
January 2020 in “Hair therapy & transplantation” This article reviews the evolution of hair transplantation techniques, focusing on the transition from follicular unit transplantation to follicular unit extraction, and reports no new clinical results.
April 2019 in “Journal of Investigative Dermatology” In this pilot study, combined platelet-rich plasma therapies showed potential benefits for improving skin elasticity and vascular network density in morphea patients, but the small sample size limits definitive conclusions.
29 citations
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January 2010 in “Methods in Enzymology” This review discusses five genetic fate mapping methods used to study cell behaviors during development and regeneration, detailing the necessary tools and considerations without reporting new experimental results.
January 2016 in “eScholarship (California Digital Library)” This dissertation reports that horizontal basal cells in the olfactory epithelium undergo symmetric divisions balanced by population asymmetry, which supports their renewal and differentiation during tissue homeostasis and regeneration.
78 citations
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May 1989 in “The Journal of Clinical Endocrinology & Metabolism” This study found that in hirsute women, daily treatment with 200 mg spironolactone significantly reduced hair growth rates and hair shaft diameters on various body areas over 12 months.
75 citations
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September 1971 in “British Journal of Dermatology” This study found that both intralesional triamcinolone acetonide and triamcinolone hexacetonide promote continuous hair growth in alopecia areata, with effects lasting at least 9 months after a single injection.