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Different body areas have unique skin cell communication patterns, explaining why certain skin diseases occur in specific regions.

A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Vitamin D and its receptor are crucial for bone health and can be influenced by certain fats and curcumin.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.

Mice without the IL-6 gene had more hair growth after injury due to higher activity of a related protein, Stat3.

The research identified genes that explain why some sheep have curly wool and others have straight wool.

The study found that certain mutations in the vitamin D receptor can cause rickets and potentially affect hair growth.

Caribine from traditional Chinese medicine may help treat hair loss.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

New treatments for male hypogonadism are effective and should be personalized.

RANK-RANKL signaling is essential for hair growth and skin health.

Apremilast may help treat hair loss in alopecia areata.

Chemokine signaling is important for hair development.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Using neurohormones to control keratin can lead to new skin disease treatments.