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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

CDP is crucial for lung and hair follicle cell development.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Accurate diagnosis and effective oral treatment are key to managing tinea capitis and preventing its spread.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

K6hf is a unique protein found only in a specific layer of hair follicles.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Liposomes could improve how skin care products work but are costly and not very stable.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.