research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling
Cathepsin L is essential for normal hair growth and development.
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research Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double-Blind, Placebo-Controlled Trial
Spironolactone most effective for hirsutism, but has side effects.
research Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss
Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
research Melanin Pigmentary Disorders: Treatment Update
Treatments for melanin disorders exist, but more effective options needed.
research Simple and Rapid Method to Isolate and Culture Follicular Papillae from Human Scalp Hair Follicles
Researchers developed a quick and easy way to get and grow cells from the base of human hair follicles.
research Induction of Dark Keratinocytes by 12-O-Tetradecanoyl-Phorbol-13-Acetate and Mezerein as an Indicator of Tumor-Promoting Efficiency
TPA is about 50 times more effective at promoting tumors than MZ.
research Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
research Human Hair Follicle Regeneration Following Amputation and Grafting into the Nude Mouse
Human hair follicles can regenerate after removal, but with low success rate.
research A Human Folliculoid Microsphere Assay for Exploring Epithelial-Mesenchymal Interactions in the Human Hair Follicle
HFMs can help study hair growth and test potential hair growth drugs.
research The Silver Locus Product (Silv/gp100/Pmel17) as a New Tool for the Analysis of Melanosome Transfer in Human Melanocyte–Keratinocyte Co-Culture
The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
research Topical Janus Kinase Inhibitors: A Review of Applications in Dermatology
Topical JAK inhibitors may help treat some skin conditions but need more research.
research Symbiotic In Vitro Seed Propagation of Dendrobium: Fungal and Bacterial Partners and Their Influence on Plant Growth and Development
Certain fungi and bacteria help orchid seeds germinate and plants grow better.
research Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety
Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.
research Effects of Melatonin Administration on Mental Health Parameters, Metabolic and Genetic Profiles in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
Melatonin improved mental health and metabolism in women with PCOS.
research Low-Level Laser Therapy for the Treatment of Androgenic Alopecia: A Review
Low-Level Laser Therapy (LLLT) is a safe and effective treatment for common hair loss, but more research is needed to find the best power and wavelength for treatment.
research Modern Drug Delivery Strategies Applied to Natural Active Compounds
New drug delivery methods can make natural compounds more effective and stable.
research Effect of Topical Application of Raspberry Ketone on Dermal Production of Insulin-Like Growth Factor-I in Mice and on Hair Growth and Skin Elasticity in Humans
Raspberry ketone may help grow hair and improve skin elasticity.
research A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention
Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.
research The Prolactin Receptor as a Therapeutic Target in Human Diseases: Exploring New Potential Indications
Blocking the prolactin receptor might help treat various diseases, but more research is needed.
research Hair Loss in Children in South-East Nigeria: Common and Uncommon Cases
The most common causes of hair loss in children in South-East Nigeria are fungal infections and alopecia areata.
research Penetration of Minoxidil from Ethanol/Propylene Glycol Solutions: Effect of Application Volume and Occlusion
More ethanol increases minoxidil delivery, but too much lowers efficiency.
research Dihydrotestosterone Inhibits Hair Growth in Mice by Inhibiting Insulin-Like Growth Factor-I Production in Dermal Papillae
Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
research In Vivo Hair Growth Promotion Effects of Cosmetic Preparations Containing Hinokitiol-Loaded Poly(ε-Caprolactone) Nanocapsules
Cosmetics with hinokitiol-loaded nanocapsules were found to effectively promote hair growth.
research Melanocyte and Gonad Activity as Potential Severity Modifying Factors in C3H/HeJ Mouse Alopecia Areata
Gonadal hormones significantly affect the severity of alopecia areata in mice.
research Sensitive Skin
Sensitive skin often causes discomfort, affects many people, especially women and older adults, and should be managed with careful product selection.
research Engineering the Niche for Hair Regeneration: A Critical Review
Further research is needed to improve hair regeneration using stem cells and nanomaterials.
research Crystalline Cataract and Uncombable Hair Syndrome in a 7-Year-Old Girl
The study found no common cause for a girl's crystalline cataract and uncombable hair, suggesting their co-occurrence might be coincidental.
research Antibody-Capped Mesoporous Nanoscopic Materials: Design of a Probe for the Selective Chromo-Fluorogenic Detection of Finasteride
Probe detects finasteride with high selectivity and low detection limit.
research Clinical Case Notes: Tamoxifen Optic Neuropathy
A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.
research Poly(γ-Glutamic Acid)/Chitosan Hydrogel Nanoparticles for Effective Preservation and Delivery of Fermented Herbal Extract for Enlarging Hair Bulb and Enhancing Hair Growth
The nanoparticles improved hair growth and enlarged hair bulbs.