202 citations
,
June 2005 in “Aaps Pharmscitech” This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.
191 citations
,
February 2002 in “Archives of Dermatology” This review discusses herbal therapies for dermatologic disorders, focusing on those with scientific evidence of efficacy and common interactions, but reports no new clinical results.
183 citations
,
January 2018 in “Cosmetics” This review discusses side effects and allergy contact dermatitis caused by essential oils in cosmetic products and reports no new clinical results.
182 citations
,
June 2002 in “Journal of Neuroscience” This study suggests that apoE4 may contribute to cognitive decline by reducing androgen receptor levels in the brain, but androgen treatment improved memory deficits in female mice expressing human apoE4.
180 citations
,
September 1999 in “British Journal of Dermatology” This review discusses the psychological and social impacts of androgenetic alopecia and suggests that medical treatments can have some positive psychological effects, highlighting the condition's moderate stress and impact on body image.
180 citations
,
November 1991 in “American Journal of Psychiatry” This study found that fluoxetine did not demonstrate short-term efficacy in treating trichotillomania in a placebo-controlled, double-blind crossover setting.
179 citations
,
April 2012 in “Nature Communications” This study demonstrates the potential of using bioengineered follicles from adult tissue-derived stem cells for fully functional hair regeneration, illustrating possible applications in organ replacement therapy.
170 citations
,
September 2019 in “Evidence-based Complementary and Alternative Medicine” This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.
162 citations
,
July 2011 in “Biomacromolecules” This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.
159 citations
,
September 2001 in “European Journal of Cancer Care” This literature study reviews the consequences of hair loss due to chemotherapy and nursing care interventions but reports no new clinical results.
159 citations
,
July 2006 in “Endocrine Reviews” This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.
157 citations
,
May 2021 in “Endocrine Reviews” This review discusses recent advancements in understanding and managing congenital adrenal hyperplasia, including improvements in screening, diagnostics, and potential genetic and cell-based treatments, but reports no new clinical findings.
153 citations
,
October 2012 in “Skin Pharmacology and Physiology” This review discusses the use of caffeine in cosmetics for its fat-reducing, antioxidant, and hair growth properties, but reports no new research findings.
147 citations
,
January 2003 in “American journal of clinical dermatology” This review discusses various forms of ichthyosis, including genetic and acquired types, detailing their characteristics, causes, and potential management strategies, but reports no new clinical results.
142 citations
,
January 2019 in “Frontiers in Neuroendocrinology” This review summarizes proposed pathophysiological mechanisms of postpartum depression, highlighting neuroendocrine and neurobiological changes, but reports no new findings and calls for integrated understanding of the disorder.
140 citations
,
August 2011 in “Biomaterials” This study observed that keratose, derived from human hair, integrated well in mouse tissue and remodeled with collagen, suggesting potential as a non-toxic biomaterial for regenerative applications.
136 citations
,
May 2016 in “Phytotherapy Research” This systematic review suggests that turmeric and curcumin products, both oral and topical, may offer therapeutic benefits for various skin conditions, though further research is necessary to evaluate efficacy more thoroughly.
134 citations
,
February 2005 in “Neuropsychopharmacology” GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.
133 citations
,
May 2016 in “Cell Host & Microbe” In this study, human dermal fibroblasts were identified as natural host cells that support productive Merkel cell polyomavirus infection, and the MEK antagonist trametinib was introduced as an effective inhibitor to control the virus.
131 citations
,
July 2009 in “Experimental Dermatology” This review discusses the development and advances in studying trichogenic dermal cells for hair follicle morphogenesis, summarizing methods, bioassays, and molecular markers, but reports no new research findings.
129 citations
,
January 2007 in “Otology & Neurotology” This study found that delivering math1 via an adenovector led to vestibular hair cell regeneration and improved balance function in ototoxin-treated adult mice.
128 citations
,
March 2006 in “American Journal of Pathology” The study found that prolactin expressed in human scalp hair follicles acts as an autocrine modulator, inhibiting hair growth and promoting hair follicle regression, which may contribute to hair loss in hyper-prolactinemia patients.
127 citations
,
December 2005 in “Experimental Dermatology” This study provides evidence that psychoemotional stress inhibits hair growth in mice by affecting the brain-hair follicle axis, with specific neuropeptides and treatments modulating this effect.
125 citations
,
September 2001 in “The FASEB Journal” This study demonstrated that stress inhibited hair growth in mice, likely through substance P-dependent activation of immune cells, highlighting a brain-hair follicle connection.
124 citations
,
December 2016 in “Pharmaceuticals” This review discusses the functions and potential therapeutic targeting of TRP ion channels in the skin, noting their involvement in both physiological processes and various pathological conditions, but reports no new experimental results.
121 citations
,
May 2009 in “Journal of Ethnopharmacology” This study found that the methanol extract of Eclipta alba showed dose-dependent hair growth promoting activity in pigmented C57/BL6 mice by influencing the transition from the telogen to anagen phase.
119 citations
,
March 2020 in “Frontiers in Bioengineering and Biotechnology” This review provides an overview of recent tissue engineering and regenerative medicine developments in Asia, highlighting significant advances, representative research achievements, and discussing future directions, without presenting new research results.
116 citations
,
December 2017 in “International Journal of Women's Dermatology” This review discusses various treatment options for adult female acne, highlighting the need for tailored approaches due to individual patient needs and reports no clinical outcomes.
116 citations
,
May 2013 in “Proceedings of the National Academy of Sciences of the United States of America” This study discovered that the circadian clock influences hair follicle regeneration, making hair grow faster in the morning and causing more radiation-induced hair loss in the morning compared to the evening.
116 citations
,
August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.