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New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

A group has developed therapies that show promise for treating cancer and various other conditions.

ILC1-like cells can cause alopecia areata by attacking hair follicles.

Vitamin D is crucial for skin health and managing skin diseases.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.

Bicalutamide may help treat female pattern hair loss.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Adding a second method to PROTACs could improve cancer treatment.

The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.

Blocking the protein CXCL12 with a specific antibody can increase hair growth in common hair loss conditions.

Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.

The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Desmoglein 4 is controlled by specific proteins that affect hair growth.

Thyroid hormone receptors are essential for hair growth and wound healing.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Allopregnanolone changes gene expression in glioblastoma cells.

A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.