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Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

Recombinant human epidermal growth factor is versatile, effective, and safe for long-term skin and mucosal treatments.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.

New insights into cell communication in psoriasis suggest innovative drug treatments.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Effective PCOS treatments require targeting specific signaling pathways.

ILC1-like cells can cause alopecia areata by attacking hair follicles.

Maternal aspartame consumption during pregnancy leads to skin damage and higher apoptosis in newborn rat offspring.

Adding a second method to PROTACs could improve cancer treatment.

Finasteride may affect male fertility by interfering with specific sperm signaling.

Certain compounds from Kushtakudori ennai may help treat hair loss.

Noggin gene inactivation causes skeletal defects in mice, varying by genetic background.

People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.

Dermal adipose tissue in mice can change and revert to help with skin health.

Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Laminin 332 is essential for normal skin cell behavior and structure.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.

Genetic variants in PDE6H and LPAR6 cause vision impairment and hair loss in two Pakistani brothers.

Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.