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A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

The research identified genes that explain why some sheep have curly wool and others have straight wool.

Analog 23 is a promising compound for prostate cancer treatment.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.