January 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that alopecia areata and androgenetic alopecia moderately affected the quality of life of Chinese patients, with younger individuals and those experiencing hair loss for over a year reporting higher impact.
January 2014 in “Journal of Clinical Dermatology” In this study, topical minoxidil significantly improved the quality of life for females with androgenic alopecia, as measured by both the dermatology life quality index and a visual analog scale.
January 2013 in “Annals of King Edward Medical University” This study observed that androgenetic alopecia notably impacts quality of life, with women experiencing poorer outcomes than men, particularly affecting symptoms, feelings, and personal relationships.
January 2012 in “Current Therapy In Oral and Maxillofacial Surgery” Endoscopic forehead and brow lifting safely and consistently improves aged eyebrows, but may have complications.
745 citations
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February 1992 in “Trends in genetics” This article describes the potential role of various growth factors and molecules in regulating mammalian hair follicle development but does not present new experimental results.
167 citations
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January 2006 in “Gynecological Endocrinology” This study found that women with polycystic ovary syndrome reported a poorer health-related quality of life compared to women in the general population and patients with other medical conditions.
158 citations
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March 2011 in “Journal of the American Academy of Dermatology” In this study, cutaneous lupus erythematosus was associated with significantly impaired quality of life, particularly affecting emotional well-being, compared to other dermatologic and chronic medical conditions.
150 citations
,
December 2012 in “EMBO Reports” This review explores the mechanisms of adult stem cell self-renewal, using skin as a model, and reports no new results but raises important unanswered questions in the field.
101 citations
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January 2012 in “Annals of Dermatology” In this study, researchers found that androgenetic alopecia significantly harms quality of life, particularly in younger patients, those with more severe or long-term alopecia, and those who have sought non-medical hair care.
95 citations
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July 2016 in “Journal of The American Academy of Dermatology” This review concluded that patients with alopecia areata consistently show poor health-related quality of life scores, similar to those in other chronic skin diseases like atopic dermatitis and psoriasis.
86 citations
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May 2011 in “Journal of The American Academy of Dermatology” This study found that patients with alopecia perceive their hair loss as more severe than dermatologists do, and their own ratings of hair loss severity better reflect their quality of life impacts.
79 citations
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March 2017 in “Dermatologic clinics” This review discusses the complex systemic nature of vitiligo and its associations with autoimmune conditions, emphasizing the need for increased understanding and awareness of related comorbidities and psychological effects.
75 citations
,
February 2017 in “Aging” This study found that treating mtDNA mutator mice with the antioxidant SkQ1 delayed aging traits and extended their lifespan, potentially by alleviating mitochondrial dysfunction caused by reactive oxygen species.
71 citations
,
July 2015 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with PCOS have elevated serum androgen levels throughout adulthood, with these levels decreasing and variations increasing as they approach menopause.
61 citations
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April 2021 in “Frontiers in Medicine” This study found that hidradenitis suppurativa significantly impaired quality of life in German patients, with severity linked to skin and certain extra-cutaneous changes, but not reduced by surgical or conventional medicamentous treatments.
58 citations
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January 2018 in “International Journal of Women's Dermatology” This review discusses the psychological impact of alopecia on women and reports no new clinical findings, highlighting the effect on self-esteem and quality of life.
50 citations
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December 2010 in “Bjog: An International Journal Of Obstetrics And Gynaecology” This study found that Sri Lankan women with polycystic ovary syndrome experienced higher psychological distress and poorer health-related quality of life, primarily linked to hirsutism rather than obesity.
49 citations
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July 2021 in “Nutrients” This review explores lifestyle modifications for women with polycystic ovary syndrome, discussing dietary, physical, and supplementation strategies, but reports no new clinical results.
45 citations
,
January 2013 in “Dermatology Research and Practice” This study found that patients with alopecia areata experience significantly poorer quality of life compared to the general population, affecting mental health, social functioning, and overall health outcomes.
45 citations
,
January 1999 in “Dermatology” This study validated the VQ-Dermato, the first dermatology-specific quality of life instrument in French, and found it to be reliable, acceptable for routine use, and more responsive than the SF36.
44 citations
,
August 2010 in “Journal of Investigative Dermatology” Alopecia areata seriously lowers quality of life, especially affecting self-image, mental health, and social life.
43 citations
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March 2019 in “JAMA Dermatology” This study found that persistent chemotherapy-induced alopecia is often more severe and diffuse than alopecia from endocrine therapy, with both conditions negatively impacting patients' emotional wellbeing, and moderate to significant improvement was observed with dermatologic therapy.
40 citations
,
December 2011 in “British Journal of Dermatology” This article reviews how chronological aging affects female scalp hair growth and suggests that multiple factors, including environmental influences, contribute to female pattern hair loss; no new clinical results are presented.
39 citations
,
January 2023 in “Journal of the European Academy of Dermatology and Venereology” This review found that alopecia areata significantly impairs quality of life, particularly through embarrassment and self-consciousness, in children and adolescents.
37 citations
,
January 2010 in “International Journal of Trichology” This study concluded that heredity is associated with hair loss, while lifestyle and stress factors are not significantly related.
37 citations
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August 2009 in “Journal of the American Academy of Child & Adolescent Psychiatry” This article discusses the impact of trichotillomania on children, highlighting significant impairment and distress, but reports no new clinical findings.
31 citations
,
August 2021 in “Stem Cell Research & Therapy” This review examines the life cycle, biomarkers, and functions of hair follicle stem cells, emphasizing their role in hair loss therapy and other skin and hair disorders, but reports no new clinical results.
31 citations
,
November 2000 in “Clinical and Experimental Dermatology” This study developed the Women's Androgenetic Alopecia Quality of Life Questionnaire, which shows high reliability and internal consistency for assessing the impact of AGA on women's quality of life.
29 citations
,
October 2020 in “eLife” This study using Mendelian randomization in UK Biobank data suggests that lifelong increased free testosterone may have mixed effects, including increased bone density and prostate cancer risk, warranting well-powered trials to address uncertainties.
26 citations
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March 2001 in “PubMed” This article reviews the effect of aging on male hormone levels and fertility, highlighting the need for more research on the benefits and risks of androgen supplementation in older men.