This article reviews the cutaneous side effects of immune checkpoint inhibitors and targeted therapies for skin cancers, noting that while generally mild, these effects can influence treatment decisions and quality of life, underscoring the need for physicians to be aware of these adverse reactions.
9 citations
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April 1987 in “International Journal of Dermatology” This article reviews rosacea and rosacea-like demodicidosis, discussing historical findings, but provides no new clinical results; the authors highlight the role of Demodex in related skin conditions.
179 citations
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October 2018 in “American Journal of Clinical Dermatology” This review outlines various dermatologic adverse events associated with targeted therapies and immunotherapies, emphasizing the need for collaboration between dermatologists and oncologists to manage these effects effectively; it reports no new clinical findings.
3 citations
,
July 2017 in “Elsevier eBooks” This article reviews the identification and assessment of cutaneous drug reactions, emphasizing the importance of early recognition and the need for accurate diagnosis to prevent serious complications; it reports no new clinical results.
12 citations
,
March 2021 in “JAAD Case Reports” This study reported that immunotherapy in cancer patients can lead to skin-related immune adverse events, such as rashes, pruritus, and vitiligo, affecting a substantial proportion of patients.
1 citations
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July 2021 in “Clinical Cosmetic and Investigational Dermatology” This case study reports a misdiagnosis of secondary syphilis with probable neurosyphilis as PLEVA in a 12-year-old, highlighting the importance of considering syphilis in patients with unusual symptoms.
May 2014 in “Clinical and Experimental Dermatology” A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.
This chapter discusses the mechanisms, presentation, course, differential diagnosis, and treatment of drug-induced skin reactions and reports no new clinical results.
December 2023 in “Revista de la Facultad de Ciencias Médicas (Quito)” This case report describes a 15-year-old female whose initial systemic lupus erythematosus manifestations were fever and rash appearing separately, illustrating diagnostic challenges between SLE and infection.
March 2022 in “The Journal of Family Practice” Following treatment plans is crucial to prevent worsening skin and hair conditions.
4 citations
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January 2012 in “Elsevier eBooks” The document concludes that various skin conditions have specific treatments, ranging from antihistamines for urticaria to surgery and medication for tumors and chronic skin diseases.
132 citations
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July 2000 in “Lupus” This study found that chronic cutaneous lupus erythematosus with discoid lesions was the most common skin manifestation among patients with lupus erythematosus, while nonspecific skin lesions were linked to systemic lupus erythematosus, particularly during active disease phases.
32 citations
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September 2015 in “Dermatology” This study describes a newly recognized skin reaction associated with dasatinib, nilotinib, and ponatinib, marked by a lichenoid exanthem with severe pruritus that may necessitate discontinuation of therapy.
November 2021 in “Chattagram Maa-O-Shishu Hospital Medical College Journal” This descriptive study reported that Chronic Cutaneous Lupus Erythematosus was the most prevalent subtype, highlighting distinct clinical and pathological features among Cutaneous Lupus Erythematosus subtypes.
March 2019 in “Nasza Dermatologia Online” A man had both alopecia areata and lichen planus, which is uncommon.
January 2017 in “Springer eBooks” This article reviews the classification, pathogenesis, and treatment options for cutaneous lupus erythematosus and reports no new clinical findings.
1 citations
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January 2019 in “Skin appendage disorders” This case report highlights that new onset non-scarring alopecia after allogeneic stem cell transplantation may indicate chronic graft-versus-host disease.
149 citations
,
July 2002 in “Dermatologic clinics” This review discusses the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus, reporting no new clinical findings.
60 citations
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September 2013 in “Alimentary Pharmacology & Therapeutics” This review discusses the dermatological adverse events from immunosuppressive and anti-TNF therapy in IBD, finding increased risks of non-melanoma skin cancer and other skin conditions, and recommends regular cancer screening.
42 citations
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April 2012 in “Seminars in Oncology” This review discusses the skin side effects associated with targeted cancer therapies and reports no new clinical results; it emphasizes the need for empirical management based on expert opinion.
39 citations
,
January 2012 in “Acta dermato-venereologica” This study examined 27 DRESS patients diagnosed in Thailand, identifying phenytoin, allopurinol, and nevirapine as common causes, with a 3.7% mortality rate and systemic corticosteroids being a common treatment.
32 citations
,
September 1989 in “Medical Clinics of North America” This review describes the types of skin lesions associated with systemic lupus erythematosus, discussing their histopathological features, serologic associations, pathogenesis, and prognostic implications.
16 citations
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July 2002 in “Australasian Journal of Dermatology” This case report illustrates the risk of skin necrosis in patients with high antiphospholipid antibody levels after stopping anticoagulation therapy, highlighting the necessity for careful monitoring.
9 citations
,
September 2016 in “Dermatologic Surgery” This study identified a new subtype of lichen planopilaris that mimics androgenetic alopecia, selectively affecting vellus hair follicles and presenting unique histopathological features.
7 citations
,
June 2015 in “Cutaneous and Ocular Toxicology” This study attempts to classify histomorphologic reactions to drugs to aid in diagnosing drug eruptions, which are common in hospitalized patients but lack specific diagnostic features.
4 citations
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January 2012 in “Chemical Immunology” This paper discusses the challenges of diagnosing drug eruptions, emphasizing the nonspecific patterns and unclear pathomechanisms, and calls for further research using new biologic drugs to understand these reactions better.
1 citations
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November 2021 in “Advances in Dermatology and Allergology” This study described the clinical and pathologic characteristics of patients with cutaneous lupus erythematosus, noting that chronic cutaneous lupus was most common, with photosensitivity as a prevalent symptom.
This study reports an increase in the frequency and variety of skin conditions associated with COVID-19, noting that milder cases often present with pernio-like lesions, while severe cases may involve livedo racemosa, retiform purpura, and acral ischemia.
January 2023 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This review details skin conditions in children and adolescents related to the SARS-CoV-2 pandemic, emphasizing mask-related acne and various cutaneous manifestations linked to infection and vaccination, with most being mild or nonspecific.
This study found that in the Indian population, SLE patients with only skin manifestations often had a positive immunological profile, suggesting early identification of disease before systemic symptoms develop.