26 citations
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March 2001 in “PubMed” This article reviews the effect of aging on male hormone levels and fertility, highlighting the need for more research on the benefits and risks of androgen supplementation in older men.
4 citations
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September 2006 in “European Urology Supplements” Dutasteride reduces DHT and improves BPH symptoms more effectively than finasteride.
July 2025 in “Biotechnology and Bioprocess Engineering” Spirulina extract may effectively promote hair growth and reduce inflammation, offering a natural alternative for hair loss treatment.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found that both oral and topical formulations of VISPOTM, a saw palmetto oil, significantly reduced hair fall and increased hair density in subjects with androgenetic alopecia, with no serious adverse effects observed.
Topical finasteride may better target hair follicles without significant benefits over oral form.
August 2024 in “JEADV Clinical Practice” In this clinical trial, 16 women with frontal fibrosing alopecia experienced significant improvements in hair density, vellus hair count, and quality of life after monthly intralesional dutasteride treatments, though larger and longer-term studies are needed to confirm these findings.
August 2025 in “JAAD International” Bicalutamide may reduce hair shedding in women but needs longer trials to confirm its effectiveness.
3 citations
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January 2022 in “Scientific Reports” This study found that SAMiRNA-AR68, a nanomedicine targeting androgen receptor mRNA, increased hair counts in androgenetic alopecia patients with no observed side effects.
1 citations
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November 2023 in “Journal of Ayurveda and Integrative Medicine” In this study, a topical Ashwagandha serum significantly improved hair growth, density, thickness, and quality of life in adults with mild to moderate hair loss compared to a placebo, demonstrating potential as an effective and safer alternative treatment for alopecia.
September 2024 in “Advanced Biomedical Research” This study compared auriculotherapy, Aslagh capsule, and metformin in women with PCOS, finding auriculotherapy significantly improved menstrual cycle duration and excess hair growth more than the other treatments, though all reduced these symptoms.
August 2024 in “Nutrients” This study found that a combination of probiotic strains of Lactiplantibacillus administered over 16 weeks reduced the number and density of telogen hairs in individuals with androgenic alopecia, while increasing the abundance of Lactobacillus in their gut microbiota.
June 2024 in “Trends in Urology & Men s Health” This study explores the controversial condition known as post‐finasteride syndrome, observed in some men who experience lasting sexual, neurological, and psychological side effects after stopping finasteride, emphasizing its rarity and the lack of proven treatments.
November 2024 in “Journal of Family Medicine and Primary Care” This review highlights that 5 Alpha Reductase Inhibitors, used for treating conditions like benign prostatic hypertrophy, can cause side effects that sometimes persist after stopping the medication, urging physicians to consider these drugs as potential sources of new symptoms in patients.
September 2023 in “Cureus” This study found that Dr. SKS Hair Booster Serum significantly improved hair shaft diameter, terminal hair counts, and hair growth rate in women with PCOS experiencing female pattern hair loss, without any reported adverse events, over a six-month treatment period.
19 citations
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June 2021 in “The world journal of men's health” This review examines the negative effects of anabolic-androgenic steroid use on the male reproductive system, including impaired testosterone production, sperm production issues, and adverse metabolic consequences without reporting new clinical results.
16 citations
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November 2021 in “Antioxidants” This review examines the role of oxidative stress in male hypogonadism associated with noncommunicable chronic diseases and discusses various management strategies, but it presents no new clinical findings.
15 citations
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December 2006 in “Clinical interventions in aging” This analysis of the Prostate Cancer Prevention Trial found that finasteride reduces prostate cancer risk by nearly 25% and enhances the PSA test's ability to detect prostate cancer and high-risk diseases.
14 citations
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May 2016 in “Therapeutic advances in urology” This review examines the use of tadalafil and finasteride as a combined therapy for BPH, suggesting it may effectively reduce treatment-related sexual adverse events and improve symptom relief.
8 citations
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January 2011 in “Korean Journal of Andrology” This study found that combining 4 mg doxazosin with 0.2 mg tamsulosin improved urinary symptoms with fewer vasodilatory side effects compared to a higher dose of doxazosin in hypertensive males with LUTS.
1 citations
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January 2012 in “Daehan namseong gwahag hoeji” This study found that dutasteride was more effective than finasteride in reducing total prostate volume and PSA levels and improving symptoms in patients with benign prostate hyperplasia.
December 2025 in “Current Issues in Molecular Biology” This study evaluated novel steroids' potential as future hormonal therapies for neuroprotection in glucose disorders, but emphasized that further research is needed to optimize androgen antagonist use in the context of COVID-19 progression.
December 2025 in “Actas Dermo-Sifiliográficas” Bicalutamide may improve hair growth in postmenopausal women with mild side effects.
November 2025 in “Journal of Cosmetic Dermatology” This study found that a proprietary saw palmetto (Serenoa repens) extract significantly increased hair growth and reduced hair shedding in men and women with self-perceived thinning hair over a 90-day period, compared to placebo, without reported adverse events.
November 2025 in “ACS Omega” This study found that compounds from *Tectona grandis* leaves showed moderate inhibition of steroid 5α-reductase, a factor in androgenetic alopecia, and exhibited anti-inflammatory properties by inhibiting nitric oxide and pro-inflammatory cytokines IL-1β and IL-6 in vitro, suggesting potential dual-action benefits for AGA management.
May 2025 in “Clinical Endocrinology” In this study, metformin was found to reduce prolactin levels in men with hyperprolactinemia and normal hair growth but not in those with androgenic alopecia, suggesting that androgen excess may interfere with metformin's effects on prolactin.
January 2025 in “Anais Brasileiros de Dermatologia” This review examines male androgenetic alopecia and reports no new clinical results, offering insights to aid dermatologists in making informed therapeutic decisions.
January 2025 in “JAAD International” This randomized, controlled clinical trial found that combining 25 mg/d bicalutamide with 1 mg/d minoxidil for 24 weeks did not enhance hair density improvement in female pattern hair loss compared to 1 mg/d minoxidil alone, with no significant difference observed between the groups.
September 2024 in “Journal of Cutaneous and Aesthetic Surgery” This review focuses on the pharmacological properties, indications, contraindications, and safety profile of bicalutamide, a non-steroidal androgen receptor antagonist, in dermatological research, particularly its off-label use for improving female pattern hair loss as measured by Sinclair grading.
August 2023 in “Medicina-lithuania” This review discusses the degenerative effects of anabolic-androgenic steroids on the nervous system and reports no new experimental results, aiming to increase public awareness of their health risks.
October 2021 in “Cosmoderma” This review summarizes existing knowledge on diffuse and patterned alopecia, emphasizing recent advancements in treatment beyond FDA-approved options, but it reports no new clinical findings.