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Chemotherapy with docetaxel can cause painful nail and skin side effects that may lead to stopping treatment.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Certain maturity signs appear before and after the first release of sperm in boys.

Androgen deprivation therapy doesn't lower the risk of death from COVID-19 in prostate cancer patients.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.

A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

The document concludes that breast pain should be managed with personalized treatment, starting with non-drug methods and progressing to medication if necessary, while considering side effects and patient needs.

Antiandrogens help treat hormone-related conditions in both men and women.

Liarozole may be more effective than cyproterone acetate for treating advanced prostate cancer, with better PSA response and survival rates, while maintaining quality of life.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Medical treatments like chemotherapy and radiotherapy can harm sperm production, so freezing sperm before treatment is important for men who want children later.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

New treatments for male hypogonadism are effective and should be personalized.

Finasteride helps reduce priapism in sickle cell anemia patients.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

As of 1994, treatments for liver cancer had not significantly improved patient survival.

Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.

Current research explores hair growth drugs, while future research aims for personalized treatments.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Scalp cooling effectively prevents severe hair loss in breast cancer patients treated with docetaxel and is safe.

Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.