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Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

This study provides further evidence for a genetic basis of PCOS, showing that polycystic ovarian morphology is a marker of inherited biochemical features in families with PCOS.

This study found that cutaneous manifestations are prevalent in PCOS patients, with 68% experiencing symptoms like hirsutism and acne, highlighting the need for better awareness across medical specialties.

This article reviews polycystic ovary syndrome in adolescents, highlighting its endocrine and metabolic features, and reports no new clinical findings; the etiology may involve early-life abnormalities in androgen production.

In this study, researchers identified specific long non-coding RNAs involved in feather development that do not follow traditional genetic inheritance patterns in chickens.

In this study, correlations between urinary and serum androgen metabolites were examined in girls aged 6-13, revealing that summed urinary metabolites strongly correspond with circulating androstenedione and testosterone levels, though individual variations depend on participant characteristics such as age and body measurements.

This study found that salivary testosterone levels were significantly lower in oligospermic and azoospermic men compared to normal men, suggesting its potential use in assessing male androgen status.

This study found that women with polycystic ovary syndrome in the Black Sea Region had higher levels of androgens, obesity, and insulin resistance, increasing their risk of metabolic syndrome compared to healthy women.

This article discusses congenital adrenal hyperplasia due to 21 hydroxylase deficiency as a cause of ambiguous genitals in 46XX individuals and reports no new research findings.

This case study reports that immunotherapy with ipilimumab and nivolumab induced hypophysitis in a patient with renal cell carcinoma, emphasizing the need for careful monitoring of endocrine function in such treatments.

This report discusses the challenges of interpreting bone mineral density in transgender individuals undergoing hormone therapy and highlights the lack of guidelines for assessing fracture risk or BMD results in this population.

This study found that women with female pattern androgenic alopecia have significantly higher levels of certain androgens and androgen sulfates compared to normal premenopausal women, suggesting markers for diagnosis and treatment efficacy.

The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.

This review discusses the challenges in measuring testosterone for assessing androgen excess in women and emphasizes the importance of quality control in laboratory methods, but it reports no new clinical results.

This study found that Bacillus/Trapa japonica fruit ferment filtrate extracts enhanced human hair follicle dermal papilla cell proliferation through the Akt/ERK/GSK-3β signaling pathway, suggesting potential benefits for alopecia treatment.

This study found that Eclipta alba extracts exhibit significant antimicrobial activity against various human pathogens, including antibiotic-resistant strains, suggesting potential use in treating infectious diseases.

This review examines current and potential approaches to managing chronic wound inflammation through macrophage-targeted strategies using ECM-inspired wound dressings, but it reports no new clinical results.

This study isolated a bioactive peptide from Trapa japonica fruit and found that it may protect human dermal papilla cells from DHT-induced stress, suggesting potential for biomedical applications.

In this chemical investigation, cyclospongiaquinone 1 from the sponge Verongula cf. rigida showed strong steroid 5α-reductase inhibitory activity, comparable to that of finasteride.

This study suggests that 5-ADIOL-S may contribute to the synthesis of potent androgens in peripheral tissues, and 3 alpha-DIOL-S could be a marker of androgen metabolism in various female patient groups.

This study found that in a mouse model of PCOS, high androgen levels caused pyroptosis in ovarian granulosa cells and increased ER stress in oocytes, reducing oocyte maturation rates, while treatment with CPA and DMF improved these rates.

This study found that in a mouse model of bronchopulmonary dysplasia, minoxidil administered at 50 mg/kg/day did not impact lung development or inhibit lysyl hydroxylation.

This study found that mice exposed to low humidity showed altered epidermal gene expression, which was modulated by topical emollient application; this suggests emollients may help manage dry skin in low-humidity environments by affecting specific gene pathways.

This study suggests that specific structural features of minoxidil analogs, such as hydrophobic and hydrogen bond field contributions, are key to enhancing lysyl hydroxylase inhibitory activity, which could inform future hair growth treatments.

In this study, a pH-responsive microneedle patch was developed, showing potential in rat models for treating spinal cord injuries by reducing inflammation, promoting nerve regeneration, and supporting neurogenesis, which contributed to improved motor and neurological recovery.

This study concluded that current cross-sex hormone treatments for trans men and trans women are effective with a low risk of side effects in the short term, though they did observe specific clinical changes.

This review discusses recent advances in scarless wound healing, focusing on strategies to create pro-regenerative scaffolds for repairing damaged skin, and reports no new clinical results.

In this study of reproductive-aged women in Tehran, idiopathic hirsutism and polycystic ovary syndrome were reported to be prevalent, with rates influenced by the screening methods used.

Skin cells can help create early hair-like structures in lab cultures.