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The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Researchers identified specific genes that are important for mouse skin cell development and healing.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Finasteride causes lasting fertility decrease in rats.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

People with alopecia areata have higher levels of a heart disease marker than those without hair loss.

High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.

Adrenal gland disease is common in ferrets and causes hair loss and other symptoms.

Unwanted facial hair significantly impacts over 40% of women's psychological and social well-being, and various treatment options are available.

Metabolic syndrome in kids and teens is linked to obesity and increases diabetes and heart disease risk; early lifestyle changes are crucial for management.

Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Non-thermal plasma treatment makes mouse skin thicker and increases growth factors without harming the tissue.

Larger ovarian size is linked to higher insulin resistance in women with PCOS.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.