96 citations
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September 1975 in “The Journal of Clinical Endocrinology & Metabolism” In this study, significant elevations of DHA and testosterone were associated with pubic hair development and voice changes in boys during puberty.
June 2019 in “The Medical journal of Basrah University” This study found that laparoscopic ovarian drilling effectively decreased LH and testosterone levels, aiding fertility in PCOS patients nonresponsive to certain medications, without negatively impacting ovarian reserve.
93 citations
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June 2001 in “The Journal of Clinical Endocrinology and Metabolism” This study found that serum androgen levels in premenopausal women may be influenced by genetic variants of the androgen receptor and estrogen receptor β genes.
9 citations
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October 2018 in “Medical Science Monitor” In this study, oral finasteride therapy was associated with decreased DHT levels and improved hair loss severity in young male AGA patients, while hormonal changes influenced the curative effect.
1 citations
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January 2020 In this study, researchers found that serum anti-Mullerian hormone levels in adolescents with polycystic ovary syndrome were not influenced by body mass index.
9 citations
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June 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
4 citations
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January 2018 in “JBRA assisted reproduction” This study found that orlistat significantly reduced weight and total testosterone levels in Iranian women with polycystic ovary syndrome after 12 weeks of treatment.
2 citations
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September 2021 in “Universal Journal of Pharmaceutical Research” This study found significant associations between polycystic ovary syndrome and increased serum levels of reproductive hormones, as well as connections to infertility, hirsutism, and metabolic syndrome in Yemeni women.
18 citations
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January 1985 in “Acta Obstetricia Et Gynecologica Scandinavica” In this study of hirsute women, researchers found that correlations between hirsutism and hyperandrogenism were observed only in patients with a low LH/FSH ratio.
12 citations
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May 2005 in “Fertility and Sterility” This study suggests that insulin levels may influence ovarian volume in women with idiopathic hirsutism who have normal ovulatory cycles and androgen levels.
September 2019 in “Mağallaẗ Tikrīt li-l-ʻulūm al-ṣirfaẗ” This study reported that women with polycystic ovary syndrome had significantly higher concentrations of oxytocin, testosterone, luteinizing hormone, prolactin, and follicle-stimulating hormone compared to healthy controls.
29 citations
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January 1998 in “Dermatology” This research reports that many acne patients have elevated androgen levels, contributing to a cycle that may lead to polycystic ovarian disease and potentially sterility.
2 citations
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March 2020 in “Baghdad Science Journal” This study found that among men with Benign Prostatic Hyperplasia, treatment with the 5α-reductase inhibitor finasteride for three months significantly reduced levels of dihydrotestosterone and estradiol, hormones involved in prostate enlargement, without altering follicle-stimulating hormone or luteinizing hormone levels.
2 citations
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January 2017 in “Iraqi journal of medical sciences” This study found that serum zinc levels were significantly decreased in obese women with polycystic ovary syndrome compared to their non-obese counterparts.
1 citations
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November 2024 in “World Journal of Biology Pharmacy and Health Sciences” This study observed that in infertile females, those with PCOS had higher BMI, increased LH levels, and altered LH/FSH ratios compared to non-PCOS females, although no significant correlation was found between BMI and hormone levels among the PCOS group.
1 citations
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July 2016 in “Mağallaẗ Kulliyyaẗ al-ṭibb Baġdād” This study found that women with polycystic ovary syndrome had significantly higher levels of prostate-specific antigen, which positively correlated with testosterone levels, the LH/FSH ratio, and hirsutism severity.
This study found that women with polycystic ovary syndrome had significantly higher levels of the protein fetuin-A compared to healthy controls.
January 2022 in “Research Square (Research Square)” This study determined that serum AMH levels are higher in women with PCOS compared to controls and may serve as a diagnostic marker for ovarian dysfunction alone or with other tools.
This study examined serum PSA levels in women with androgenetic alopecia to evaluate their potential as a marker for androgen effects on target organs.
2 citations
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July 2019 in “Pakistan Journal of Biological Sciences” This study suggests that perforin/granzyme-B might play a role in the interaction of sex hormones in patients with polycystic ovary syndrome.
12 citations
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January 2016 in “Journal of Assisted Reproduction and Genetics” This study suggests that genetic variations in the AMH signal pathway may be linked to susceptibility and phenotype variations in PCOS among women with insulin resistance.
5 citations
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August 2018 in “Sexual Medicine Reviews” In this review and meta-analysis, the authors concluded that 5α-reductase inhibitor therapy is not consistently associated with significant increases in serum testosterone levels in men.
13 citations
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May 1998 in “The Journal of Clinical Endocrinology & Metabolism” This study found that hCG decreased 5α-reductase and androgen receptor levels in skin samples from women in vitro, suggesting that human skin responds to LH/hCG treatment.
June 2025 in “Journal of Kufa for Chemical Sciences” In this study, researchers observed increased hormone levels such as testosterone and LH in both obese and non-obese women with Polycystic Ovary Syndrome, but concluded that the enzyme 3βHSD shows poor diagnostic value for PCOS compared to healthy women.
May 2024 in “Journal of drug delivery and therapeutics” This study found that women with polycystic ovarian syndrome at a gynecology clinic in Nnewi exhibited significant oxidative stress and hormonal imbalances compared to controls.
January 2021 in “Journal of Shaheed Suhrawardy Medical College” This study found that treatment with oral contraceptives containing 35mg ethinylestradiol and 2mg cyproterone acetate significantly reduced serum AMH levels in women with clomiphene citrate-resistant polycystic ovary syndrome, unlike metformin.
145 citations
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March 2010 in “Fertility and Sterility” This study reported that ovulatory PCOS is a milder form of the condition compared to classic PCOS phenotypes, which share similar clinical and hormone characteristics.
39 citations
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August 2001 in “Clinical endocrinology” This study found that lean women with PCOS have a similar degree of tissue insulin resistance as obese women with PCOS, suggesting that insulin resistance may be a primary feature of the syndrome.
27 citations
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April 2017 in “European journal of endocrinology” This retrospective study found that serum hormone levels and MRI detection of ovarian nodules contributed to distinguishing virilizing ovarian tumors from ovarian stromal hyperthecosis in postmenopausal women, though histopathology remains crucial for diagnosis.
10 citations
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May 2009 in “Cases Journal” This case study reports that a virilizing Leydig cell type ovarian tumor in a 40-year-old woman caused hyperandrogenism and virilization symptoms, which improved post-surgery.