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Flutamide caused damage to male rat reproductive organs and may affect fertility.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

The document explains how male reproductive hormones work and affect the body.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Oestrogens are key for bone growth during puberty in both boys and girls.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Lowering testosterone speeds up wound healing in male mice.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

PDRN helps repair tissue and improve wound healing with a high safety profile.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

New genes found linked to balding, may help develop future treatments.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

Arachidonic acid helps hair grow by increasing growth factors and improving follicle health.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.