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Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.

People in Jeddah know about Vitamin D and its sources but are unclear on how much they need daily, and while many women take supplements, attitudes towards increasing Vitamin D levels vary.

Venous catheterization may help diagnose the cause of female hyperandrogenism when imaging is unclear.

Certain medications can reduce sexual desire and function, especially in women.

GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.

Finasteride in male rats causes liver and metabolic issues in their offspring.

A woman's high testosterone levels and related symptoms improved after ovary removal surgery.

A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride may help treat childhood brain tumors by activating certain genes.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

A woman's mature cystic teratoma caused her virilization by producing testosterone.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.