research Curcumin Derivatives Inhibit Testicular 17β-Hydroxysteroid Dehydrogenase 3
Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.
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research Testosterone in COVID-19: An Adversary Bane or Comrade Boon
Testosterone's effects on COVID-19 are unclear and need more research.
research Nestin as a Marker of Unipotent Epithelial Progenitor Cell Differentiation into Outer Root Sheath Keratinocytes in Embryonic and Adult Hair Follicles
Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
research Nestin as a Marker of Unipotent Embryonic and Adult Progenitors Differentiating into an Epithelial Cell Lineage of the Hair Follicles
Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.
research The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators, and Myostatin Inhibitors
Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.
research Protective Effect of DA-9401 in Finasteride-Induced Apoptosis in Rat Testis: Inositol Requiring Kinase 1 and c-Jun N-Terminal Kinase Pathway
DA-9401 helps protect rat testis from finasteride damage.
research Advances in Male Hormone Substitution Therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Exposure of Xenopus Laevis Tadpoles to Finasteride, an Inhibitor of 5-Alpha Reductase Activity, Impairs Spermatogenesis and Alters Hypophyseal Feedback Mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research New Insights Into Testosterone Biosynthesis: Novel Observations From HSD17B3 Deficient Mice
Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
research Evaluation of the 5α-Reductase Inhibitor Finasteride on Reproduction and Gonadal Development in Medaka, Oryzias Latipes
Finasteride negatively affects fish reproduction and gonadal development.
research A Case of Familial Male-Limited Precocious Puberty with a Novel Mutation
A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.
research Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility
Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
research Spontaneous Fertility in a Male Patient with Testotoxicosis Despite Suppression of FSH Levels
A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.
research Morphometric-Stereological and Functional Epididymal Alterations and a Decrease in Fertility in Rats Treated with Finasteride and After a 30-Day Post-Treatment Recovery Period
Finasteride causes lasting fertility decrease in rats.
research Exploring Hormone Therapy Effects on Reproduction and Health in Transgender Individuals
Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.
research Molecular Basis of Androgen Action on Human Sexual Desire
Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
research Semen Parameters Among Transgender Women With a History of Hormonal Treatment
Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.
research Unchanged Androgen-Binding Properties of Sex Hormone-Binding Globulin in Male Patients with Liver Cirrhosis
SHBG binding properties are unchanged in male liver cirrhosis patients.
research The Effect of Finasteride on the Secretion of Testosterone, DHT, LH, FSH, and Tissue Factors in the Testis of NMRI Mice
Finasteride reduces sperm count and quality and alters hormone levels in mice.
research Testosterone Supplementation for Aging-Associated Sarcopenia
Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.
research Salivary Testosterone Levels in Infertile Men
Men with low or no sperm count have lower salivary testosterone levels, and saliva testing can measure their testosterone well.
research Reproductive Performance of Hair Ewes and Rams Implanted With Melatonin Previous to the Anestrus Season in Northwest Mexico
Giving melatonin to sheep before the non-breeding season can improve their chances of reproducing in northwest Mexico.
research Sex Hormones and Frailty in Older Men: The Osteoporotic Fractures in Men (MrOS) Study
Older men with lower levels of available testosterone are more likely to be frail.
research Steroidogenesis of the Testis: New Genes and Pathways
New genes and pathways are important for testosterone production and male sexual development.
research Male Hormonal Contraception: Looking Back and Moving Forward
New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
research Nutrition and Acne: The Role of Diet in Acne Development
Diet, especially dairy and high-sugar foods, can cause acne.
research Reproductive System, Male: Biology of Spermatogenesis and Toxicology
The document explains how sperm cells are produced, the role of testosterone in this process, and how toxins can reduce sperm count and fertility.
research Epigenetic Effects of Finasteride on Human Leydig Cells
Finasteride may cause lasting sexual issues by altering specific genes in human cells.
research Effect of Rosemary Extract on Some Internal Organs of Young Male Albino Rats: A Histological Study
High doses of rosemary extract can harm the liver, kidneys, and reproductive organs in young rats.
research PNKP Is Required for Maintaining the Integrity of Progenitor Cell Populations in Adult Mice
PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.