16 citations
,
October 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study found that dutasteride may offer neuroprotection in early-stage Parkinson's disease by preventing loss of striatal dopamine and altering steroid levels in MPTP-lesioned mice.
3 citations
,
April 2010 in “Clinical Neuropharmacology” In this case report, a 75-year-old man with benign essential blepharospasm and Parkinson disease experienced significant symptom relief from dystonia after starting finasteride, suggesting it may be a potential therapeutic option.
2 citations
,
January 2018 in “PubMed” This case report describes a 45-year-old man with a pituitary macroadenoma whose symptoms and tumor size improved significantly after one month of treatment with cabergoline.
12 citations
,
May 2005 in “Journal of the American Geriatrics Society” This case report describes successful treatment of valproate-induced hyperammonemia in a 79-year-old man using lactulose, marking the first such documented use for this condition.
4 citations
,
March 2002 in “International journal of toxicology” In this study on tolerant rats, maternal and developmental toxicity from levo-alpha-acetyhnethadol hydrochloride were observed at all doses, without specific fetal toxicity or teratogenic effects.
10 citations
,
October 2016 in “Epilepsy & behavior” In this study, behavioral disturbances were commonly observed with levetiracetam, while somnolence was frequently reported with oxcarbazepine among patients with refractory epilepsy.
June 2026 in “The Journal of Steroid Biochemistry and Molecular Biology” This study concluded that combining letrozole with cabergoline improved ovulation and clinical pregnancy rates in patients with polycystic ovarian syndrome and hyperprolactinemia compared to letrozole alone.
May 2024 in “Nano letters” This study developed a quercetin-encapsulated and polydopamine-integrated nanosystem that reshapes the perifollicular microenvironment, showing potential for rescuing hair follicle viability and regenerating hair follicles in androgenic alopecia by scavenging reactive oxygen species and promoting angiogenesis.
January 2017 in “Corpus Université Laval (Université Laval)” This study found that dutasteride may offer neuroprotective effects on dopaminergic neurons in an animal model of early-stage Parkinson's disease, suggesting potential therapeutic use.
65 citations
,
October 2015 in “Acta Biomaterialia” This study found that using a pH-sensitive layered double hydroxide nanocarrier to deliver etoposide significantly reduced liver toxicity and enhanced the drug’s effectiveness in targeting and suppressing non-small cell lung cancer.
79 citations
,
January 1982 in “The American Journal of Medicine” This study reports that VP-16-213 (etoposide) shows significant therapeutic activity in several cancers including small cell bronchogenic carcinoma and certain leukemias, with hematologic toxicity being the primary side effect.
June 2026 in “The Egyptian Journal of Neurology Psychiatry and Neurosurgery” This review discusses the potential of mesenchymal stem cells and their secretome, mainly extracellular vesicles, in Parkinson's disease therapy, highlighting their neuroprotective abilities and therapeutic prospects, but it reports no clinical results.
25 citations
,
March 2012 in “Journal of oncology pharmacy practice” This case report describes an elderly multiple myeloma patient whose hair repigmentation was associated with lenalidomide use, suggesting hair graying may be reversible.
35 citations
,
April 2012 in “Journal of Clinical Psychopharmacology” Finasteride reduces gambling symptoms in Parkinson's patients.
April 2023 in “Dermatology practical & conceptual” This study concluded that lenalidomide significantly induces the proliferation and migration of melanocyte stem cells, enhancing their differentiation into functional melanocytes in a mouse model.
2 citations
,
January 2007 in “Toxicologie Analytique et Clinique” This case study observed a massive lithium overdose in a 38-year-old woman with bipolar disorder, who survived despite extremely high lithium concentrations through continuous venovenous hemodiafiltration.
2 citations
,
March 2020 in “Cns & Neurological Disorders-drug Targets” In this study, researchers analyzed lurasidone's risk profile for treating schizophrenia and bipolar depression, identifying unlisted adverse reactions like hypersexuality, restless leg syndrome, thrombocytopenia, and telogen effluvium, which show probable or possible correlations with the drug.
October 2019 in “Asian College of Neuropsychopharmacology” 1 citations
,
July 2022 in “Frontiers in Pharmacology” This study found that dutasteride may help prevent enteric neuronal damage in an animal model of Parkinson's disease, highlighting its potential for drug repurposing to address neuroinflammation.
6 citations
,
October 2021 in “Brain Sciences” This study reported that dutasteride, identified through a drug repurposing strategy, showed the potential to reduce neuroinflammation and cognitive impairment in LPS-stimulated models.
August 2026 in “Canadian Journal of Health Technologies” This study found that Litfulo improved hair regrowth in patients aged 12 and older with severe alopecia areata but did not meaningfully improve anxiety or depression symptoms compared to placebo.
1 citations
,
June 2023 in “Radiation oncology journal” This study suggests that low-dose radiotherapy may lead to temporary neurological improvements in some Alzheimer's patients, with 20% showing cognitive improvement at 6 months; it was well-tolerated, though larger trials are needed for confirmation.
October 2015 in “Elsevier eBooks” Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.
August 2025 in “Tropical Journal of Natural Product Research” In this study, LEON gel—an innovative nanoliposome-based delivery system for lavender essential oil—showed significant hair growth acceleration in male white rats without causing irritation, suggesting enhanced effectiveness compared to traditional essential oil use.
16 citations
,
June 1983 in “Journal of Neurochemistry” This study found that copper injections increased dopamine-β-hydroxylase activity in the brains of mottled mice, an animal model for Menkes' syndrome.
2 citations
,
January 2023 in “Pharmaceuticals” This study found that in male mice, microglial changes due to a Parkinson's-like lesion were influenced by sex hormones, with dutasteride treatment preventing some effects.
January 2024 in “Wiadomości Lekarskie” This source reports that clinical trials using advanced Deep Brain Stimulation systems, augmented with AI to integrate kinematic data, eye tracking, and cognitive assessments, show promise in improving diagnostic accuracy and monitoring symptoms for patients with Parkinson's disease.
This study concluded that the combination of all-trans-retinoic acid and tocopherol-α is not recommended for treating del(5q) myelodysplastic syndromes due to low efficacy and high incidence of adverse effects.
15 citations
,
June 2019 in “Biochemical Journal” This study identified a heterozygous de novo mutation in the ODC1 gene causing a new disorder characterized by overgrowth and developmental delay, and suggests that DFMO treatment may help manage elevated ODC activity and putrescine levels.