10 citations
,
January 2023 in “Molecular and Cellular Biochemistry” This review discusses the potential therapeutic role of the edible plant Solanum nigrum for managing COVID-19 symptoms and post-COVID complications based on in silico docking and pharmacological studies, but reports no new clinical results.
10 citations
,
June 2019 in “Journal of Tissue Engineering and Regenerative Medicine” This study found that cultured mouse dermal papilla (mDP) cells can induce hair follicle neogenesis in de novo regenerated skin tissues grafted onto mice.
10 citations
,
January 2016 in “Elsevier eBooks” This chapter reviews the role of nanoparticles in wound healing, exploring current therapies, developments, and future directions, but reports no new clinical results.
10 citations
,
September 2015 in “PLoS ONE” This case report documents a female toddler with novel compound heterozygous mutations in the VDR gene causing hereditary 1,25-dihydroxyvitamin D-resistant rickets, expanding the known mutation spectrum for this disease.
10 citations
,
August 2014 in “PLoS ONE” This study suggests that mammalian hair follicles may serve as a viable and non-invasive system for diagnosing traumatic brain injury, reflecting similar molecular responses observed in other tissues.
10 citations
,
June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified FP-1 as a highly specific extracellular matrix protein in follicular papilla cells, which may play a role in hair growth regulation during specific hair cycle phases.
10 citations
,
January 2003 in “Journal der Deutschen Dermatologischen Gesellschaft” In this study, hydroxychloroquine treatment in patients with scleromyxoedema led to complete or partial remission of skin symptoms and improved mobility, though it did not affect paraproteinaemia.
10 citations
,
January 1985 in “Elsevier eBooks” Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
10 citations
,
May 1978 in “Acta Dermato Venereologica” In this study, seven patients with generalized toxic erythema developed sterile pustules localized to hair follicles or sweat ducts, with most having a history of medication, solvent exposure, or infection.
9 citations
,
May 2024 in “Cureus” This review discusses the role of platelet-rich plasma in assisted reproductive technology for enhancing endometrial receptivity and reports promising outcomes.
9 citations
,
December 2023 in “Journal of Neuroimmune Pharmacology” This study found that systemic administration of NDP-MSH, a melanocortin receptor agonist, provided neuroprotective effects on dopaminergic nigrostriatal neurons in a mouse model of Parkinson's disease, reducing neuroinflammation and suggesting a role for regulatory T cells in these neuroprotective effects.
9 citations
,
January 2023 in “International Journal of Biological Sciences” This study suggests that CTHRC1, a protein expressed in cardiac fibroblasts, may improve wound repair and prevent cardiac rupture after myocardial infarction by activating a specific signaling pathway.
9 citations
,
April 2021 in “Evidence-based complementary and alternative medicine” This study found that Guilu Erxian Glue significantly alleviates various doxorubicin-induced side effects in mice, enhancing exercise capacity and reducing oxidative stress and inflammation.
9 citations
,
February 2020 in “International Journal of Endocrinology” This study found that men with early-onset androgenetic alopecia and certain risk factors may have worse gonadal steroidogenesis and an increased likelihood of developing gonadal dysfunction, suggesting a male equivalent of polycystic ovarian syndrome.
9 citations
,
May 2019 in “Experimental Cell Research” This study found that Hedgehog signaling likely contributes to cervical carcinogenesis, and while itraconazole reduced growth in mice, it did so through pathways other than inhibiting Hedgehog signaling.
9 citations
,
July 2018 in “Current Pharmaceutical Design” This review discusses the importance of heme oxygenase in skin physiology and disease, but it reports no new clinical results; the authors highlight its potential as a treatment target for conditions like atopic dermatitis and psoriasis.
9 citations
,
February 2013 in “Hormone and Metabolic Research” This study reported that CYP21A2 heterozygous mutations do not significantly contribute to the pathogenesis of polycystic ovary syndrome.
9 citations
,
March 2011 in “Oxidative stress and disease” This review explores herbal medications for skin disorders, covering their clinical efficacy, safety, and common drug interactions, but reports no new clinical results.
9 citations
,
May 2008 in “Journal of Clinical Oncology” This article compiles references on toxic epidermal necrolysis and cutaneous reactions to anticancer agents but reports no new findings.
9 citations
,
May 2005 in “Expert Review of Clinical Immunology” This article examines anticytokine therapies for autoimmune diseases, highlighting the potential of anti-interferon-γ as a universal treatment for certain conditions and noting varying effectiveness of tumor necrosis factor-α inhibitors.
9 citations
,
January 2005 in “Experimental dermatology” The researchers observed that normal murine hair follicles are direct targets for melatonin, with receptor expression varying throughout the hair cycle, suggesting melatonin's role in hair cycle control.
9 citations
,
August 2002 in “Current Opinion in Pediatrics” This article discusses the roles of pediatrics and dermatology departments at Yale University School of Medicine, but reports no specific clinical results.
8 citations
,
June 2024 in “APOPTOSIS” In this review, researchers discussed recent insights into caspases, enzymes initially associated with cell death and inflammation, revealing their broader roles in cell proliferation, migration, and differentiation, and highlighting the importance of caspase knock-out mice for understanding their implications in diseases.
8 citations
,
February 2023 in “American Journal of Physiology-Cell Physiology” This review discusses the roles of adiponectin and bradykinin in skin homeostasis and pathologies, highlighting the need for further research into their therapeutic potential but reports no new clinical results.
8 citations
,
January 2022 in “Burns and trauma” This review discusses the role of extracellular vesicles from specific skin cells in wound healing, emphasizing their potential in regenerative medicine and reporting no new experimental results.
8 citations
,
December 2021 in “International Journal of Family Studies, Food Science and Nutrition Health” This review discusses the potential health benefits and applications of extra virgin olive oil as a nutritional therapeutic immune-enhancer, but reports no new clinical findings.
8 citations
,
June 2021 in “International Journal of Molecular Sciences” In this study, UCMSC exosomes showed protective effects against cisplatin-induced hearing loss in mice by improving hearing and promoting cochlear tissue repair.
8 citations
,
March 2021 in “Medicina-lithuania” This review discusses the use of platelet-rich plasma for treating female androgenetic alopecia, reporting that it shows high patient satisfaction and improved quality of life in affected women.
8 citations
,
October 2019 in “Immunological investigations” This study suggests that the rs2075876 variant in the AIRE gene may significantly increase susceptibility to alopecia areata in the examined male population.
8 citations
,
September 2017 in “Journal of Natural Medicines” This study reported that the n-butanol fraction of Perilla frutescens extract, particularly rosmarinic acid, showed potential for hair regrowth and anti-androgenic activity in male mice, suggesting it as a possible treatment for androgenetic alopecia.