14 citations
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January 1982 in “International journal of radiation biology & related studies in physics, chemistry & medicine” In this study, irradiation with different ionizing particles in rabbit forebrains showed that higher LET values accelerated early expression and late deterioration of forebrain damage.
13 citations
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December 2018 in “Development, Growth & Differentiation” This study found that male and female chicken feather morphology and color patterns can be extrinsically modified through molting and resetting the stem cell niche during regeneration.
12 citations
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February 2025 in “Women s Health” This paper reports that while metformin may improve fertility outcomes and reduce miscarriage rates in women with PCOS, its efficacy can differ depending on the specific treatment combination used.
10 citations
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February 2017 in “European journal of neuroscience/EJN. European journal of neuroscience” This study found that local synthesis of 17β-estradiol and 5α-dihydrotestosterone, combined with specific stimulation patterns, is crucial in determining the direction and strength of long-term synaptic effects in the hippocampal CA1 region of male rat slices.
10 citations
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June 2006 in “Fertility and Sterility” This article discusses the diverse symptoms and treatment options for polycystic ovary syndrome, emphasizing diligent management of its metabolic component, but reports no new findings.
6 citations
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August 2023 in “Fertility and Sterility” This review details the 2023 International Guideline update for assessing and managing polycystic ovary syndrome, which provides evidence-based recommendations to improve care and patient outcomes but notes the remaining low to moderate quality of evidence.
5 citations
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October 2022 in “Heliyon” This review discusses infertility in polycystic ovary syndrome and therapeutic options, without reporting new results; it underscores the importance of personalized treatment plans based on patient needs and disease characteristics.
5 citations
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October 2012 in “Journal of Midwifery & Women's Health” This article reviews infertility diagnosis and initial management for advanced practice clinicians, emphasizing the role of midwives and advanced practice nurses, but reports no new clinical findings.
4 citations
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November 2023 in “Acta obstetricia et gynecologica Scandinavica” In this guideline update, researchers emphasized refining diagnostic criteria for polycystic ovary syndrome using ultrasound or hormone levels, while highlighting a healthy lifestyle's importance without specific diet recommendations, and reviewed treatments with a focus on comorbidities and pregnancies from a Nordic standpoint.
3 citations
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January 2022 in “Journal of neuroendocrinology” This study found that Arc/Arg3.1 expression in hippocampal neurons is regulated by sex steroids in a sex-dependent manner, with E2 increasing expression in females and DHT in males.
3 citations
,
August 2021 in “Nutrition research” This study suggests that estrogen regulates vitamin A metabolism in skin tissues in a sex-dependent manner, which may have implications for treating acne, hair loss, and skin immunity.
2 citations
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May 2025 in “Frontiers in Pharmacology” In this study, analysis of FDA data revealed a substantial risk of dermatologic adverse events with aromatase inhibitors, especially anastrozole and exemestane, highlighting the importance of dermatologic monitoring during such therapies.
2 citations
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February 2022 in “Frontiers in Endocrinology” This study found that antiandrogenic pretreatment with combined oral contraceptives did not improve ovulation and pregnancy outcomes compared to direct letrozole induction in women with PCOS.
1 citations
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May 2022 in “Research Square (Research Square)” The study demonstrates that acetate treatment may alleviate PCOS-associated depression in rats by reducing neuroinflammation and modifying epigenetic changes in the brain.
1 citations
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November 2024 in “Expert Opinion on Drug Safety” In this retrospective pharmacovigilance study, researchers analyzed over 7,900 adverse event reports related to aromatase inhibitors, identifying common side effects and toxicological mechanisms to highlight potential safety concerns in treating postmenopausal hormone receptor-positive breast cancer.
1 citations
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December 2017 in “Research for Rural Development/Research for Rural Development (Online)” This study found no correlation between clinical signs and sex steroid levels in ferrets with hyperadrenocorticism and noted that androstenedione was elevated in many cases.
1 citations
,
May 2016 in “The Nurse Practitioner” This article reviews current guidelines for diagnosing, treating, and providing holistic care for women with polycystic ovary syndrome, without presenting new clinical findings.
1 citations
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December 2015 in “Endocrinology” This study suggests that dietary decanoic acid may manage hyperandrogenism and insulin resistance in PCOS, as observed in animal and cell model experiments.
1 citations
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April 2015 in “The FASEB Journal” This study found that perinatal androgen deprivation in male rats increased serum estrogen levels and enhanced exploratory behavior, indicating that elevated estrogen may affect brain sex differentiation and related behaviors.
September 2026 in “Clinical Cosmetic and Investigational Dermatology” This case report highlights the diagnostic challenges in a patient with atypical lupus erythematosus tumidus due to long-term misdiagnosis and conflicting pathological findings, with effective treatment achieved using hydroxychloroquine and methylprednisolone.
March 2021 in “Annals of Translational Medicine” This report presents two cases of systemic lupus in male patients with a distinct form of alopecia that combines both scarring and non-scarring elements, highlighting the variability in lupus-related hair loss presentations.
December 2025 in “Preprints.org” This study investigated bovine milk-derived exosomes and found they significantly increased dermal papilla cell viability and up-regulated WNT pathway components in human hair follicles, suggesting potential therapeutic value for hair loss disorders like androgenetic alopecia and telogen effluvium.
August 2025 in “Stem Cell Research & Therapy” This study found that exosomes from human umbilical cord mesenchymal stem cells significantly promoted hair follicle growth and enhanced the transition to the growth phase in a model of androgenetic alopecia, by enriching specific microRNAs that activate key pathways involved in hair regeneration.
March 2025 in “Journal of Endocrinology and Metabolism” This study found that while rat models treated with letrozole and dihydrotestosterone exhibit altered sterol, leukotriene, and steroid hormone profiles similar to human PCOS, significant differences remain.
April 2026 in “AMEI's Current Trends in Diagnosis & Treatment” This review discusses the symptoms, causes, and treatment options for polycystic ovary syndrome and reports no new results; the authors highlight the role of lifestyle changes, medications, and fertility treatments.
March 2026 in “Anti-Aging Eastern Europe” This review examines current evidence on personalized management strategies for PCOS, but does not present new clinical results; the authors advocate for treatments tailored to predominant symptoms and individual health profiles.
August 2025 in “Obstetrics and gynecology.” This article reviews the management of polycystic ovarian syndrome, highlighting lifestyle modification and individualized pharmacological treatment strategies, and reports no new clinical results.
May 2025 in “International Journal of Trichology” In this case report, the researchers observed scalp alopecia due to metastasis of breast cancer in a woman in her sixties, highlighting that scalp metastases can result in patchy hair loss and, although often accompanied by poor prognosis, can sometimes show comparatively better outcomes.
October 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study examined lipid changes in rat models of polycystic ovarian syndrome, finding that letrozole and dihydrotestosterone treatments led to some lipid alterations similar to human PCOS, while other changes were unique to the models.
April 2024 in “Canadian Women s Health Today” This review suggests that "polycystic ovarian syndrome" is a misleading name, as the disorder involves complex metabolic and reproductive issues beyond ovarian dysfunction and may stem from factors affecting the fetus in utero.