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120-150 / 1000+ resultsresearch Decision letter for “Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls”
research Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction
The researchers found that corneodesmosin is crucial for maintaining skin barrier integrity and hair follicle architecture in mice, with its deletion leading to severe skin and hair abnormalities.
research Zinc metabolism in lethal-milk mice
This study found that supplementing zinc improved certain developmental defects in mice with the lethal-milk mutation, although it did not increase the survival rate among backcross progeny.
research Regarding prostate-specific antigen: let's not shoot the messenger
This study found that 5α-reductase inhibitors significantly reduced low-grade prostate cancer incidence in men but nearly doubled the incidence of high-grade prostate cancers.
research Reply to the Letter to the Editor “Androgen deprivation therapy may constitute a more effective prophylactic than therapeutic strategy in COVID-19 patients” by N. Bennani and I. M. Bennani-Baiti
Androgen deprivation therapy might help prevent severe COVID-19, but more research is needed.
research Reply to letter to the editor: “A response to ‘Male balding is a major risk factor for severe COVID-19’”
This article discusses potential links between male balding, specifically androgenic alopecia, and severe COVID-19, suggesting that balding may serve as a biomarker for identifying higher-risk patients, but it reports no new experimental findings.
research Response to Letter to the Editor
This commentary highlights the debate on the role of inflammation and fibrosis in androgenetic alopecia, contrasting various studies' findings without reporting new results.
research Fronteggiare l’inaffidabilità della letteratura da studi clinici
This article discusses the limitations of relying on literature and regulatory documents for pharmaceutical evidence, proposing public health decisions be based on independent trials like those by the Mario Negri Institute.
research An autosomal recessive nonsense variant in the EGFR gene induces perinatal lethality in “Blonde d'Aquitaine” calves
The researchers reported finding a recessive nonsense variant in the EGFR gene responsible for perinatal lethality in the "Blonde d'Aquitaine" cattle breed, prompting the development of a screening test to help eradicate this genetic flaw.
research In response to the letter to the editor by Soha Ghanian et al. re our publication “Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in European males”
This paper reports no new results; it addresses the effects of Dutasteride on testosterone and DHT in men, and discusses the implications for androgen deprivation and COVID-19 outcomes.
research COMMENTS ON THE LETTER ON HYPONATREMIA ASSOCIATED WITH DIURETIC USE AND URINARY RETENTION IN AN OLDER MAN
This article highlights the complexity of diagnosing hyponatremia in older adults, emphasizing the need to evaluate urinary tract obstruction, medication effects, and age-related changes rather than relying solely on spot urinary values.
research Certificate of Appreciation Award Letter to Professor Jasna Lipozen?i?
research President's letter
This paper reflects on a meeting in Nashville emphasizing the evolution of hair restoration surgery into a distinct medical specialty, but reports no new scientific findings.
research Response to the letter to the editor; Androgenetic alopecia; drug safety and therapeutic strategies
Use finasteride over dutasteride for hair loss; consider topical treatments and weigh risks.
research Response to Letter: “Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss”
Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.
research Solanum nigrum L. in COVID-19 and post-COVID complications: a propitious candidate
This review discusses the potential therapeutic role of the edible plant Solanum nigrum for managing COVID-19 symptoms and post-COVID complications based on in silico docking and pharmacological studies, but reports no new clinical results.
research Immunopharmacological potential of Arctium lappa L. in immune-mediated skin diseases: A critical review of experimental and clinical evidence
This review explores the immunopharmacological potential of A. lappa for inflammatory musculoskeletal disorders (IMSDs) but reports no new clinical results, emphasizing the need for standardized research methodologies.
research Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
This study found that combined loss of Atr and p53 in adult mice led to severe tissue degeneration and delayed regeneration due to the accumulation of highly damaged cells.
research KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype
This study found that simultaneously inhibiting both KLK5 and KLK7 proteases completely rescued skin barrier defects in a mouse model of Netherton syndrome, suggesting both should be therapeutic targets.
research Harlequin ichthyosis (ichq): a juvenile lethal mouse mutation with ichthyosiform dermatitis.
This study suggests that the harlequin ichthyosis mouse model closely resembles human type 2 harlequin ichthyosis, indicating its potential as a useful model for studying the human condition.
research Foliar and Root Applications of Vegetal-Derived Protein Hydrolysates Differentially Enhance the Yield and Qualitative Attributes of Two Lettuce Cultivars Grown in Floating System
This study found that biostimulant application in lettuce cultivation led to significant yield and phytochemical enhancements, with effects varying between green and red cultivars depending on the treatment method used.
research Enhancing germination performance and vigor of lettuce and napa cabbage seeds through simple seed priming techniques under controlled conditions
In this study conducted under controlled laboratory conditions, warm water and shallot extract were found to significantly speed up the germination of lettuce and napa cabbage seeds compared to untreated seeds, though further testing is needed in nursery or field settings.
research Raw data from JAAD research letter: Androgenetic alopecia present in the majority of patients hospitalized with COVID-19: The “Gabrin sign”
This study reports that a majority of patients hospitalized with severe COVID-19 in three Madrid hospitals exhibited androgenetic alopecia, termed the "Gabrin Sign".
research Conditional epidermal expression of TGFβ1 blocks neonatal lethality but causes a reversible hyperplasia and alopecia
This study found that conditional expression of TGFβ1 in mice affects epidermal and hair follicle growth, with chronic expression causing severe alopecia and a negative feedback loop involving Smad7.
research Deadly hairs, lethal feathers – convergent evolution of poisonous integument in mammals and birds
This review discusses the use of hairs and feathers as defensive tools through toxin incorporation in certain mammals and birds and reports no new experimental findings.
research Upadacitinib for management of alopecia areata and rheumatoid arthritis: Letter to the editor
This study reports a case where a patient with rheumatoid arthritis and alopecia areata saw significant improvement in both conditions after switching to daily upadacitinib treatment, specifically achieving complete hair regrowth within six months.
research Scalp rupture-related acute hair matting in a child: A case letter
In this clinical case report, a 10-year-old girl developed acute hair matting three weeks after scalp trauma and frequent povidone-iodine use, suggesting that scalp injuries and antiseptic overuse can be risk factors for this condition, especially when hair care is poor.
research 9 Signs You Sell Fake Jerseys Seized By Customs Letter Cheap for a Living
This abstract acknowledges the distress of hair loss in women, highlighting its misunderstanding, without reporting any new research findings.
research 554 Repurposing a clinical antimalarial for the therapeutic induction of lethal ER stress targeting BRAF-kinase inhibitor-resistant malignant melanoma
This study identified mefloquine as a potent inducer of lethal ER stress that effectively eliminated vemurafenib-resistant and sensitive melanoma cells, suggesting its potential for repurposing as a melanoma treatment.