Umbilical cord blood is a valuable source of stem cells for medical treatments, but its use is less common than other transplants, and there are ethical issues to consider.
3 citations,
April 2022 in “Biomolecules” Higher miR-34a levels and the A variant of the MIR-34A gene are linked to increased risk and severity of alopecia areata.
29 citations,
March 2001 in “Clinics in Dermatology” Steven Kossard classified lymphocyte-related hair loss into four patterns, each linked to different types of baldness.
18 citations,
March 2022 in “Drug design, development and therapy” Platelet-rich plasma (PRP) may help with various hair loss types, but more research is needed to find the best use method.
33 citations,
May 2018 in “Stem Cell Reports” Krt15+ cells in the mouse intestine resist radiation and can start tumors.
5 citations,
October 2016 in “Anais Brasileiros de Dermatologia” A man from Brazil had a rare case of leprosy on his scalp, which improved with treatment.
59 citations,
October 2016 in “Clinics in dermatology” Precise skin sampling is crucial to understand the role of P. acnes in acne.
18 citations,
July 2006 in “British Journal of Dermatology” Connexin 30 is usually absent in normal skin but can appear in certain skin conditions.
December 2024 in “Pharmaceutics” Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.
51 citations,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
September 2014 in “Journal der Deutschen Dermatologischen Gesellschaft” Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.
5 citations,
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.
65 citations,
January 2018 in “Nature Reviews Endocrinology” Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
1 citations,
August 2023 in “The Journal of Pathology” Different types of skin fibroblasts have unique roles in skin health and disease.
January 2008 in “Springer eBooks” Thyroid hormone may be useful for treating various skin conditions and needs more research.
76 citations,
February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
10 citations,
January 2003 in “Journal der Deutschen Dermatologischen Gesellschaft” Hydroxychloroquine helped improve scleromyxoedema in patients, but caused side effects in some.
January 2018 in “Stem cell biology and regenerative medicine” The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
19 citations,
October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.
48 citations,
April 2008 in “Human Molecular Genetics” Progerin affects cell shape but not hair or skin in mice.
October 2023 in “Apollo medicine” The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
1 citations,
November 2022 in “Pharmaceutical research” The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.
6 citations,
November 2021 in “Frontiers in immunology” STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
2 citations,
May 2023 in “Frontiers in immunology” Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
7 citations,
January 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” NIPP1 is important for healthy skin and could help treat skin inflammation.
November 2022 in “Journal of The Pakistan Dental Association” Oral ulcers are common in SLE patients and often link to other symptoms.
4 citations,
December 2022 in “International Journal of Molecular Sciences” Zinc is crucial for skin health and treating various skin disorders.
2 citations,
December 2023 in “International journal of molecular sciences” Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
8 citations,
July 2008 in “Facial Plastic Surgery Clinics of North America” More men are getting non-surgical cosmetic treatments due to increased income and social acceptance, with less invasive options being preferred.
6 citations,
August 2022 in “The Italian Journal of Pediatrics/Italian journal of pediatrics” New genetic mutations linked to rare skin disorders were found in three newborns.